Skin Cancer (Nonmelanoma)

Using a novel combination, a new study suggests another way to inhibit the hedgehog signaling pathway to prevent or delay resistance to vismodegib in patients with basal cell carcinoma.

A new study finds cutaneous human papillomavirus infection can increase the risk of squamous-cell carcinoma, a nonmelanoma skin cancer.

Researchers have shown that patients who use nonsteroidal anti-inflammatory drugs like aspirin and ibuprofen are less likely to develop three types of skin cancer.

The US Food and Drug Administration (FDA) announced the approval of vismodegib (Erivedge), for the treatment of advanced basal cell carcinoma, the most common type of skin cancer, for patients who are not eligible for surgery or radiation, and for metastatic disease.

Using in vitro techniques and mouse models, scientists at the University of Chicago Department of Medicine and colleagues have demonstrated that downregulation of PTEN in epidermal keratinocytes predisposes skin to ultraviolet B (UVB)-induced tumorigenesis.

Older male patients who have undergone heart transplant are at a higher risk for developing squamous cell carcinoma post-surgery. In addition, certain immunosuppression agents can increase the risk of basal cell carcinoma.

The imaging technique has the potential to measure the extent and depth of skin lesions.

A virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive Cancer Center–James Cancer Hospital and Solove Research Institute. Their findings were published online June 25, 2009, by the Journal of Investigative Dermatology.

According to a 2005 survey conducted by the American Academy of Dermatology, 92% of the respondents understood that getting a tan from the sun is dangerous. Yet, 65% said that they think they look better when they have a tan.

A study published in the Journal of the American Academy of Dermatology (44:807-813, 2001) reported an almost 90%

A 38-year-old man consults for a small subcutaneous nodule of approximately 2 cm in diameter. Surgical excision of the tumor nodule is performed. What is your diagnosis?

A 34-year-old, ostensibly healthy Caucasian male presented with a 3 cm × 3 cm solitary skin lesion located on the distal portion of the dorsal aspect of the right arm. What is this lesion?

A 67-year-old African American female presented with an approximately 18-month history of a solitary, asymptomatic lesion on the right leg. This patient most likely has what tumor on her leg?