Triple-Negative Breast Cancer
CONFERENCE REPORT • Treatment Combinations for HER2-Postive Breast Cancer
Cancer Network presents exclusive coverage of the 30th Annual Miami Breast Cancer Conference. We speak with nationally recognized breast cancer specialists and bring you their insights into the optimal multidisciplinary management of patients with breast cancer and the application of innovative approaches to practice.
REVIEW ARTICLE • Tumor Biology Trumps Anatomy in Breast Cancer Brain Metastases
Elgene Lim, Nancy U. Lin; ONCOLOGY Vol. 26 No. 7
This review will focus on the breast cancer subtypes with the highest incidence of breast cancer brain metastases and will characterize differences in the clinical behavior of brain metastases that arise from these different subtypes.
• Brain Metastasis in Breast Cancer: Last Barrier to the Cure?
REVIEW ARTICLE • What We Know and Issues to Be Resolved
Carey Anders, Lisa A. Carey; ONCOLOGY Vol. 22 No. 11
This review will focus on the molecular and clinicopathologic features, epidemiology and risk factors, prognosis, and current and future therapeutic strategies for patients diagnosed with triple-negative breast cancer, including a brief discussion of intracranial disease.
Researchers have identified a marker of DNA damage that may be able to predict a patient’s response to platinum-based chemotherapy agents such as cisplatin and carboplatin. The marker identified by researchers—telomeric allelic imbalance—has the potential to predict whether a patient with triple-negative breast cancer will respond to platinum-based chemotherapy.
RESEARCH REPORT • Triple-Negative Breast Cancer Characterized in Younger Breast Cancer Patients
Sixteen percent of all breast cancers are triple-negative breast cancers. Researchers in Canada have sequenced and analyzed over 100 triple-negative breast tumors at the time of diagnosis, the first in-depth genomic analysis of this heterogeneous breast cancer subtype.
REVIEW ARTICLE • Development of PARP Inhibitors: An Unfinished Story
Elizabeth A. Comen, Mark Robson; ONCOLOGY Vol. 24 No. 1
This review will examine the current understanding of PARP inhibition as a treatment for breast cancer, ongoing clinical trials, and future directions for this new approach.
• PARP Inhibitors: What We Know and What We Have Yet to Know
Genomic Subtypes in Choosing Adjuvant Therapy for Breast Cancer
Amelia B. Zelnak, MD, MSc1, Ruth M. O'Regan, MD1
, March 11, 2013
Additional insight into the biology of ER-positive breast cancers, particularly the higher risk luminal B cancers, could aid in identifying potential targets and new, effective therapies. And though the majority of triple-negative breast cancers are the “basal-like” subtype, significant proportions are in other subtypes.
• Omics as Useful
Tools in Clinical Practice: Are We There Yet?
• The Evolving Role
of Multi-Gene Tests in Breast Cancer Management
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Next Generation Treatment for Triple-Negative and Basal-Cell Breast Cancer
, March 9, 2011
The early promise of treating triple-negative and basal-cell breast cancers with poly (ADP-ribose) polymerase (PARP) inhibitors is yet to be realized, according to Lisa A. Carey, MD, who will be delivering a presentation on treatment options for these patients at the Miami Breast Cancer Conference this week.
May 3, 2013
Platinum-based chemotherapy may be the best bet for thwarting aggressive triple-negative breast cancer, according to a preliminary study. More »
April 8, 2013
March 9, 2013
At the 30th Annual Miami Breast Cancer Conference, Lisa Carey, MD, presented the major questions in managing triple-negative breast cancer. This type... More »
January 24, 2013
Researchers discovered that in triple-negative breast cancer, an inhibitor of metastasis, miR-708, is repressed, results that could lead to novel... More »
December 21, 2012
The risk of triple-negative breast cancer appears to be lower for women who delayed childbirth and who chose to breast feed according to a new study. More »
Showing 1 - 5 of 30 results.
FROM PHYSICIANS PRACTICE
Five Steps to Improving Patient Access Judy Capko,
May 21, 2013
Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.
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