The intratumoral vasculature of high-grade serous ovarian cancer does not appear to undergo significant changes during disease progression.
In a large international study, pre-AML cases had greater clonal expansion and enrichment of specific gene mutations; origins of AML were detected > 5 years before it developed.
Brazilian researchers say their study results “suggest the overall DNA methylation profile may be influenced by the histological subtype of thyroid cancer.”
The most common presentation among the younger patients was bleeding, and they were more likely have a family history of rectal cancer.
Treatment of high-risk melanoma with adjuvant bevacizumab following resection improves disease-free survival over standard observation, but not overall survival.
Recent use of aspirin or NSAIDs is associated with improved ovarian cancer–specific survival.
In an exclusive interview, thyroid cancer expert and surgeon Dr. Louise Davies discusses overdiagnosis and overtreatment of subclinical thyroid cancers.
Researchers identified the percentage cutoff for ALK positivity that is needed for clinical utility in ALK-positive NSCLC.
A preclinical study of ibrutinib provides compelling evidence that myeloid leukemias with mutated G-CSFR have abnormal activation of Btk.
Tumor microenvironments can induce T-cell senescence and exhaustion; Yangqiu Li et al highlight ways to reverse these states and improve immunotherapeutic efficacy.