Nanotechnological strategies are making preclinical strides toward more effective, less toxic, immunotherapies.
A study finds EWSR1-ETS in 42% of cases via complex, loop-like rearrangements, rather than by simple reciprocal translocations.
A study shows significant association between MTHFR C677T polymorphisms and risk of oral squamous cell carcinoma.
A study shows that receipt of radioactive iodine after reoperation may not be associated with improved outcomes.
A study shows that LKB1 deficiency in T cells increases gastrointestinal polyposis development.
Study shows that ctDNA levels measured by targeted deep sequencing sensitively indicate the presence of cancer.
The steep increase in thyroid cancer diagnosis has not been mirrored by increasing mortality rates and is likely due to widespread overdiagnosis of small neoplasms.
Brazilian researchers say their study results “suggest the overall DNA methylation profile may be influenced by the histological subtype of thyroid cancer.”
Tumor microenvironments can induce T-cell senescence and exhaustion; Yangqiu Li et al highlight ways to reverse these states and improve immunotherapeutic efficacy.
A team of Texas-based oncologists says their preclinical study results “demonstrate that IGF-1R and FOXC1 seem to positively regulate each other.”