A 56-year-old man presents with an intranasal mass.
Correct answer: D – Basaloid squamous cell carcinoma
Basaloid squamous cell carcinomas of the nasal cavity are not unusual. However, in small biopsies, these tumors may resemble other tumoral conditions, including salivary gland tumors, such as adenoid cystic carcinomas. By immunohistochemistry, basaloid carcinomas, may show positive staining for p40 and keratin 5/6, which could be used as an aid in the diagnosis. The prognosis and treatment will be guided by the extent of the tumor, possible nodal involvement, and deep of penetration of the tumors. Essentially staging of the tumor at the time of diagnosis is a good predictor of clinical outcome.