Oncology NEWS International Vol 13 No 10

First-Line Thalidomide/Dexamethasone Beneficial in Myeloma

October 01, 2004

NEW ORLEANS-A combination of oral thalidomide (Thalomid) and dexamethasone is sufficiently active in newly diagnosed multiple myeloma that current intravenous regimens are no longer required for most patients, S. Vincent Rajkumar, MD, associate professor of medicine, Mayo Clinic, Rochester, Minnesota, said at the 40th Annual Meeting of the American Society of Clinical Oncology (abstract 6508).

Trastuzumab Improves the Response to Neoadjuvant Chemotherapy in HER-2-Positive Breast Cancer Patients

October 01, 2004

NEW ORLEANS-Addition of trastuzumab (Herceptin) to standard anthracycline-containing chemotherapy in the neoadjuvant setting led to a dramatic increase in the frequency of pathological complete remissions in patients with operable HER-2-positive breast cancer. Aman Buzdar, MD, professor of breast medical oncology, M.D. Anderson Cancer Center, presented the results of the phase III trial at the 40th Annual Meeting of the American Society of Clinical Oncology (abstract 520).

High Circulating Tumor Cell Levels Predict Rapid Progression of Metastatic Breast Ca

October 01, 2004

NEW ORLEANS-By monitoring the levels of circulating tumor cells (CTCs) in peripheral blood, it is possible to predict which patients with metastatic breast cancer will progress rapidly while on apparently futile therapy, Daniel F. Hayes, MD, of the University of Michigan Comprehensive Cancer Center, Ann Arbor, said at the 40th Annual Meeting of the American Society of Clinical Oncology (abstract 509).

Cetuximab/High-Dose RT Bests RT Alone in Advanced H&N Ca

October 01, 2004

NEW ORLEANS-Cetuximab (Erbitux) plus high-dose radiation therapy (RT) significantly improved survival in patients with advanced head and neck cancer, compared with RT alone, according to results of an international phase III trial reported at the 40th Annual Meeting of the American Society of Clinical Oncology (abstract 5507).

CAD System Boosts Early Detection of Breast Cancer

October 01, 2004

NEW YORK-Computer-aided detection (CAD) of breast cancer using digitized mammograms could have detected malignancies at least 1 year earlier than film assessment by radiologists alone, according to findings from the Elizabeth Wende Breast Clinic, Rochester, New York.