Oncology NEWS International Vol 14 No 2

FDA Approves Abraxane for Metastatic Breast Cancer

February 01, 2005

ROCKVILLE, Maryland-Abraxane (paclitaxel protein-bound particles for injectable suspension, American Bioscience) has received Food and Drug Administration approval for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Previous therapy should include an anthracycline unless clinically contraindicated.

FEC Followed by Docetaxel Improves Breast Ca Outcomes

February 01, 2005

SAN ANTONIO-Sequential therapy with three cycles of fluorouracil, epirubicin (Ellence) 100 mg/m2, and cyclophosphamide (FEC-100) followed by three cycles of docetaxel (Taxotere) improved outcomes over six cycles of FEC alone, in node-positive breast cancer patients over the age of 50. Professor Henri Roche, Institut Claudius Regaud, Tou-louse, France, reported the results of the multicenter study from France and Belgium at the 27th Annual San Antonio Breast Cancer Symposium (abstract 27). While the study also included younger women, the significant improvements in disease-free and overall survival were limited to women aged 50 and older.

Follow-up Data Support Use of Stanford V Regimen for HD

February 01, 2005

SAN DIEGO, California-One in four Hodgkin’s disease (HD) patients has become a parent since participating in prospective trials of an experimental first-line regimen, known as Stanford V, designed to reduce toxicity from chemotherapy and radiotherapy.

Randomized Trial Validates Advantages of SNB

February 01, 2005

SAN ANTONIO-A randomized, multicenter trial from the United Kingdom has demonstrated what clinicians have instinctively felt: that sentinel node biopsy (SNB) is associated with less morbidity and better quality of life than standard axillary node surgery. Professor Robert E. Mansel, University of Cardiff, Wales, presented the results of the Axillary Lymphatic Mapping Against Nodal Axillary Clearance (ALMANAC) trial at the 27th Annual San Antonio Breast Cancer Symposium (abstract 18).

70-Gene Signature Predicts Time to Breast Ca Metastases

February 01, 2005

SAN ANTONIO-A 70-gene profile developed in Amsterdam to distinguish low-risk from high-risk women with node-negative breast cancer has been shown to be predictive for disease recurrence after surgery. Martine Piccart, MD, chair of the Breast International Group and head of the Medical Oncology Department, Institut Jules Bordet, Brussels, presented the results at the 27th Annual San Antonio Breast Cancer Symposium (abstract 38)

Imaging Guides Efforts to Improve the Therapeutic Ratio

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

Radiation Oncologists Map the Prostate to Increase the Accuracy of Intensity-Modulated Radiation Therapy

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

PET/CT Is Fast Reshaping Cancer Management,Drawing Two Specialties Together

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

New 5D Model May Predict Motion of Lung Tumors During Respiration

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

Endorectal Coils, Contrast Media Boost Accuracy of Magnetic Resonance Techniques for Prostate Cancer Diagnosis

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

PET/CT Outperforms PET or CT Alone in Imaging Non–Small-Cell Lung Cancer

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.

Gated 4D PET/CT: Improving Radiation Treatment Planning for Patients With Lung Cancer

February 01, 2005

This special supplement to Oncology News International comprises expertcommentary and selected reports from the 2004 meetings of RSNA andASTRO about new imaging techniques, with a focus on state-of-the-art magneticresonance imaging, positron emission tomography, computed tomography,and complementary modalities for improving the diagnosis, staging, andtreatment of a variety of cancers. Evident in these reports is the increasingcollaboration between the specialties of radiation oncology and diagnosticradiology as imaging technology continues to evolve.