Oncology NEWS International Vol 19 No 7

Cheson heads Lymphoma Research Foundation board

July 14, 2010

Bruce Cheson, MD, has become chair of the Lymphoma Research Foundation Scientific Advisory Board. Dr. Cheson is professor of medicine, head of hematology, and director of hematology research at the Lombardi Comprehensive Cancer Center at Georgetown University Hospital in Washington DC. His two-year term as chair began in July 2010.

SGO survey offers snapshot of gynecologic oncology

July 14, 2010

The Society of Gynecologic Oncologists conducted a demographic and practice survey and found that their members are shifting away from private practice into salaried positions. The survey also found an increase in the number of group or multispecialty practices.

Cancer survivors require quality care long after active phase of treatment

July 14, 2010

Th e cancer survivor population in the U.S. is nearing 14 million and is growing at a rate of about 10% each year. Unfortunately, cancer patients who have completed treatment do not always have access to comprehensive, follow-up care.

Who's News

July 14, 2010

ASTRO selects its 2010 class of fellows while ASCO bestows awards on international oncologists. Learn more about the latest appointments and accolades in the cancer community.

BRAF inhibition may enhance immunotherapy in melanoma

July 13, 2010

A preclinical study provides the rationale for combining BRAF-targeted therapy with immunotherapy agents in patients with BRAF mutations. These mutations activate the MAPK signaling pathway, which leads to increased oncogenic potential. The researchers showed that in BRAF-mutant melanoma cell lines, a selective BRAF inhibitor (PLX4720) blocked the MAPK pathway and increased tumor antigen expression without affecting T-cell function.

CBR gene increases risk of cardiomyopathy in pts receiving lower-dose anthracyclines

July 13, 2010

It is well known that exposure to chemotherapy or radiation therapy can result in long-term complications for childhood cancer survivors. What is less certain is why some children have to contend with these complications while others do not. Researchers at the City of Hope Medical Center in Duarte, Calif., are one step closer to fitting another piece in the survivorship puzzle: They hypothesized that there is some inherent genetic susceptibility that raises this risk.

ASCO: Selenium fails to prevent secondary lung cancer tumors

July 13, 2010

Results of a long-term intergroup study on the effect of selenium in early non-small-cell lung cancer highlight the differences between smokers and nonsmokers, and support the thesis that “good” supplements may be harmful in the presence of carcinogens.

Cytokine disruption study sheds light on increased risk for non-Hodgkin’s lymphoma in AIDS patients

July 13, 2010

HIV’s disruption of immune system function may cause the immune system cells themselves to become cancerous, NCI researchers have concluded. If so, this might explain why patients with AIDS are 100 times more likely to be diagnosed with non-Hodgkin’s lymphoma than the general population.