August 01, 1995
Article
CHICAGO--Until recently, physicians would have offered watchful waiting only to a select group of older men with localized prostate cancer. Now, because of concerns about the quality as well as the length of life, physicians are vigorously debating whether watchful waiting may be an option for men as young as the early 50s.
August 01, 1995
Article
SEATTLE--In patients with advanced epithelial ovarian cancer, CA 125 concentrations after two cycles of chemotherapy are a powerful independent predictor of survival, a Southwest Oncology Group Study (SWOG) has shown.
August 01, 1995
Article
PARIS, France--Biochemical modulators have brightened the prospects for patients with advanced gastrointestinal cancer, Scott Wadler, MD, reported at the American Radium Society annual meeting.
August 01, 1995
Article
NEW BRUNSWICK, NJ--Last month, The Cancer Institute of New Jersey welcomed Joseph Aisner, MD, as its new associate director of clinical science, and added four new physician/scientists to its staff.
August 01, 1995
Article
MIAMI BEACH, Fla--Breast cancer litigation is "a world whose activity is sometimes built upon old science, no science, or junk science," said Kenneth Kern, MD, of Hartford Hospital and the University of Connecticut School of Medicine, Farmington. In a presentation at the 12th Annual International Breast Cancer Conference, Dr. Kern offered the audience a "road map" for entry into that world.
August 01, 1995
Article
LAS VEGAS--A new, longer duration formulation of an LHRH (luteinizing hormone releasing hormone) analogue for advanced prostate cancer offers more convenient dosing and appears to be safe and effective.
August 01, 1995
Article
MIAMI BEACH, Fla--"The future of the NSABP [National Surgical Adjuvant Breast and Bowel Project] can't be built upon rejection of the past," said Bernard Fisher, MD, Distinguished Service Professor of Surgery, University of Pittsburgh School of Medicine.
August 01, 1995
Article
Need to consult a clinical pathologist in Tokyo? Trying to contact a particular urologic oncologist in Milwaukee? Looking for an epidemiologist on the Internet? The Cancer Fax Directory may be the best place to start your search.
August 01, 1995
Article
BETHESDA, Md--The three-member President's Cancer Panel heard evidence from a number of speakers that HIV-related malignancies are increasing at a significant rate.
August 01, 1995
Article
BALTIMORE--Breast cancer is preventable, says Johns Hopkins epidemiologist Jonathan Samet, MD. "But we don't yet know how to do it."
August 01, 1995
Article
BETHESDA, Md--One hundred years after W. Konrad Roentgen's discovery of the x-ray (which he refused to patent), the field of radiology continues to produce "wondrous accomplishments," such as modern digital, cross-sectional, and interventional radiology, Alexander R. Margulis, MD, associate chancellor, Special Projects, University of California, San Francisco, said at a conference sponsored by the Department of Health and Human Services.
August 01, 1995
Article
CONCORD, NH--Pharmaceutical companies were the pioneers in establishing cancer screening and information programs for their employees. This is why Jack Gentile went first to the pharmaceutical industry for help in founding the Industries' Coalition Against Cancer, an organization dedicated to encouraging corporations to initiate their own cancer screen/prevention programs or to enhance existing programs.
August 01, 1995
Article
WASHINGTON--Only a screening test that can reliably find stage I tumors will have any real impact on overall ovarian cancer mortality, and transvaginal ultrasound does not appear to fulfill that requirement. Although the technique can detect stage I ovarian cancers, its specificity is not high enough to make it useful as a general screening test, Beth Y. Karlan, MD, said at the American Cancer Society National Conference on Gynecological Cancers.
August 01, 1995
Article
SAN FRANCISCO--A retrospective study of 61 endometrial cancers, collected from patients at the City of Hope Hospital, Duarte, Calif, found that approximately 49% of the tumors had some type of DNA abnormality, Kristi Van Nostrand, MD, reported at the American College of Obstetricians and Gynecologists (ACOG) annual clinical meeting.
August 01, 1995
Article
HACKENSACK, NJ--The use of high-dose chemotherapy followed by bone marrow or stem cell transplantation (BMT) for metastatic breast cancer continues to be controversial, partially because of concerns that it is not cost effective, Christopher E. Desch, MD, said at a conference sponsored by the Northern New Jersey Cancer Center, Hackensack Medical Center.
August 01, 1995
Article
ATLANTA--Two studies from the University of Texas M.D. Anderson Cancer Center have shown that neutropenic fever can be safely and effectively managed on an outpatient basis in a select, low-risk group of patients, Edward Rubenstein, MD, said at the Third International Conference on Clinical Applications of Cytokines and Growth Factors in Hematology and Oncology.
August 01, 1995
Article
DURHAM, NC--Duke University Medical Center and ExVivo Therapies have announced a collaboration to construct and operate a cell processing center, the first on the East Coast. ExVivo is a joint venture between Applied Immune Sciences (AIS) and Rhône-Poulenc Rorer.
August 01, 1995
Article
NEW YORK--The "right" dose of pain medication is the one that works, Ronald Blum, MD, said at a conference on cancer pain sponsored by Cancer Care, Inc. But that simple maxim is not so easy to follow.
August 01, 1995
Article
BALTIMORE--A review of randomized trials shows that local recurrence rates for breast-conserving therapy are comparable to those for mastectomy for early-stage patients, Irene Gage, MD, said at a conference sponsored by Johns Hopkins Medical Institutions.
August 01, 1995
Article
BALTIMORE--Some 60% to 80% of ovarian cancer patients recur after the first round of treatment, and "only about 15% of ovarian cancer patients who test positive at second-look laparotomy survive as long as 5 years," Karl F. Hubner, MD, of the University of Tennessee, Knoxville, said at a nuclear oncology conference sponsored by the Johns Hopkins Medical Institutions.
August 01, 1995
Article
ROCKVILLE, Md--The FDA's Oncologic Drugs Advisory Committee (ODAC) has unanimously recommended approval of DaunoXome (liposomal daunorubicin) as first-line therapy for the treatment of advanced HIV-related Kaposi's sarcoma (KS). The usual treatment, a combination of Adriamycin, bleomycin, and vincristine (ABV), is not well tolerated over the long haul, especially when given with antiretroviral agents (ddI, ddC, and AZT).
August 01, 1995
Article
HR1579, introduced by Rep. Brown (D-OH), to require providers of home infusion therapy to be licensed and to limit physician referrals for home infusion therapy services in which the physician has a financial interest.
August 01, 1995
Article
WASHINGTON--President Clinton has appointed Dr. Richard D. Klausner as director of the National Cancer Institute. Dr. Klausner has served as chief, Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, since 1984. He earned his undergraduate degree at Yale and his MD from Duke.
August 01, 1995
Article
BALTIMORE--Irradiation of the chest wall following mastectomy has had an up and down history as breast cancer therapy. Now, says Allen S. Lichter, MD, director of Radiation Oncology, University of Michigan Medical Center, it is time to take another look at its value for patients with local or regional disease after surgery.
August 01, 1995
Article
MIAMI BEACH, Fla--Between 1 and 2 million women in the United States have received silicone-gel-filled implants for breast augmentation, and, based on the general population risk, about 10% will ultimately develop breast cancer.
August 01, 1995
Article
WASHINGTON--The $1 billion cut that the National Institutes of Health (NIH) had anticipated has been shelved for the time being. The Senate voted 85 to 14 on a resolution by Sen. Mark Hatfield (R-OR) to spare NIH from the need to make serious cuts in a wide variety of programs and initiatives.
August 01, 1995
Article
WASHINGTON--A report released by the Congressional Office of Technology Assessment (OTA) says that screening for prostate cancer has not yet been proven to save lives. The report concluded: "Because scientific knowledge is limited, but the consequences of prostate cancer and its treatment are serious, an informed and reasonable patient could equally well decide to have screening or forego it." Nevertheless, OTA said that it would be reasonable for Medicare to consider reimbursement for such screening.
August 01, 1995
Article
NEW YORK--Memorial Sloan-Kettering Cancer Center has launched Cancer Smart, the first consumer newsletter devoted to cancer. "Many people today have taken an increasingly bigger share of responsibility for keeping themselves healthy," said James B. Dougherty, MD, editor of Cancer Smart and associate chairman for clinical affairs, Department of Medicine. "Reading Cancer Smart is an opportunity to gain relevant information about cancer to improve their own well-being," he added.
August 01, 1995
Article
BETHESDA, Md--One of the discoverers of HIV, Robert C. Gallo, MD, is leaving the National Cancer Institute after 30 years, most recently as head of the Division of Tumor Cell Biology.
August 01, 1995
Article
WASHINGTON--Many of the patients who will die of cancer this year will receive care in the nation's intensive care units. Despite heralded advances in drug research and medical technology, fewer than one fourth of cancer patients admitted to an ICU survive for 6 months, Mark S. Gelder, MD, said at the American Cancer Society National Conference on Gynecologic Cancers.
August 01, 1995
Article
ANNANDALE, NJ--Medarex, Inc. and Ciba-Geigy, Ltd. have entered into an alliance for developing and marketing Medarex's MDX-210 Bispecific product. Medarex will be primarily responsible for development through phase II trials, and Ciba will be responsible for phase III trials, regulatory approvals, and commercial launch.
August 01, 1995
Article
MIAMI BEACH, Fla--The French response to the FDA ban on silicone breast implants was to issue a strong recommendation to plastic surgeons to stop using silicone-gel-filled implants or polyurethane prostheses. Now that stricter manufacturing controls are in place, that recommendation has been canceled, and today silicone implants are available in most European countries, Jean-Yves Petit, MD, said at the 12th Annual International Breast Cancer Conference.
August 01, 1995
Article
LOS ANGELES--In response to the questions being raised by new medical technologies and managed health care, City of Hope has established its Institute for Applied Health Care Ethics on its 100-acre Duarte, Calif, campus.
August 01, 1995
Article
STANFORD, Calif--Screening surgeons for HIV to protect their patients would not be cost effective, compared to the cost of most accepted health-care interventions, says Dr. Douglas Owens, professor of health research and policy, Stanford University School of Medicine.
August 01, 1995
Article
MCLEAN, Va--The way clinical trials are planned and conducted often means the difference between success and failure in winning FDA marketing approval for a drug or medical device, industry leaders said at a conference sponsored by the Cambridge Healthtech Institute, Waltham, Mass.
August 01, 1995
Article
PARIS, France--Since 1991, breast cancer has been the most common diagnosis for which bone marrow transplants are performed. Therapy-related mortality has plunged to 6% or less, and the procedure's popularity has grown steadily to the point where more than a quarter of transplants for breast cancer are now done in women receiving adjuvant chemotherapy for stages II and III disease.
August 01, 1995
Article
WASHINGTON--The Health and Human Services (HHS) Office of the Inspector General (OIG) has published a final rule that implements a civil monetary penalty for physicians who refer patients to radiology, laboratory, and other facilities in which they, or a member of their immediate family, have a financial interest.
August 01, 1995
Article
BASLE, Switzerland--Sandoz Ltd. has entered into a merger agreement with Genetic Therapy, Inc (Gaithersburg, Md) with a cash tender offer valued at $295 million. The acquisition "puts Sandoz at the forefront of gene therapy technology," said Daniel Vasella, MD, CEO of Sandoz Pharma.
August 01, 1995
Article
MIAMI BEACH, Fla--Six studies of women with silicone breast implants and no personal history of breast cancer have all found a relative risk of breast cancer of less than 1.0 (range, .24 to .67).
August 01, 1995
Article
MINNEAPOLIS--Breast imaging with FDG PET can identify breast cancer with a high specificity, a German study has shown. This technique visualizes malignant tumor tissue by increased FDG (fluorine-18-fluorodeoxyglucose) uptake (see image on " FDG PET Imaging Visualizes Malignant Breast Lesions"), said Norbert Avril, MD, of the Department of Nuclear Medicine, Technical University, Munich.
August 01, 1995
Article
BALTIMORE--A number of factors can suggest whether a focal pulmonary lesion is malignant or benign, but no single test affords a quick answer, and biopsy is usually necessary to make the diagnosis, said Peter White, Jr., MD, assistant professor of medicine at Johns Hopkins University.
August 01, 1995
Article
ATLANTA--The American Cancer Society's research program has awarded a $75,000 planning grant to the Union Internationale Contre le Cancer (UICC), based in Geneva, Switzerland, to study the feasibility of conducting a long-term international study on the effects of mammography in reducing breast cancer mortality in women in their 40s.