Skip to main content
MJH Life Sciences
  • Login
  • Register
  • Login
  • Register
Home
  • ONCOLOGY
  • News
  • Blogs
  • Topics
  • Hematology
  • Image IQ
  • Podcasts
  • Videos
  • Slideshows
  • Conferences
MJH Life Sciences

SUBSCRIBE: Print / eNewsletter

Research Offers Insight on Swallowing and Voice Difficulties in Lung Cancer

  • Naveed Saleh, MD, MS
September 9, 2019
  • WCLC, Lung Cancer

Observed swallowing function and patient-reported symptoms fail to align in patients with small-cell lung cancer (SCLC), according to research to be presented on September 8, 2019, at the International Association for the Study of Lung Cancer 2019 World Conference on Lung Cancer held in Barcelona.

“It remains unknown which patients experience dysphagia or dysphonia, and what the impact of these problems are to the patient,” wrote authors, led by J. Frowen, Peter MacCallum Cancer Centre, Melbourne, Australia.

In the pilot study, dysphagia and dysphonia prevalence and health effects were examined in a low-power prospective cohort (n=12) receiving chemoradiotherapy for limited-stage SCLC. Swallowing physiology, risk of aspiration, and esophageal motility disorder were assessed using videofluoroscopy swallowing studies (VFSS). Other data included limitations to eating and drinking, as well as patient-reported swallowing and speaking issues. Data collection occurred pre-treatment and at 1, 3, and 6 months post-treatment.

Pharyngeal swallowing was safe and functional across the cohort, with no patients aspirating. In total, 6 patients had esophageal motility disorders, with 3 patients experiencing this prior to chemoradiotherapy, and 3 experiencing it post-treatment.

In patients, eating and drinking was at its worst within the one month following treatment. Specifically, 1 patient needed a tube, 2 patients needed a specially prepared diet, and 2 needed a diet of a single consistency. However, at 3- and 6-month follow-ups, these and all other patients were consuming a normal or near-normal diet.

Three patients complained of moderate or severe swallowing difficulty at 1 month post-treatment, although oropharyngeal dysphagia was absent while on videofluoroscopy swallowing studies. These patients were administered an esophageal radiation dose of ≥15.7Gy, with a maximum dose of ≥42Gy. In these patients, swallowing problems were mild or less irritating at 3- and 6-month follow-ups. Three other patients complained of moderate or severe swallowing difficulties at 3 and 6 months post-treatment, yet no relationship with radiation dose was observed in these later reporters.

The worst scores in patient-reported voice difficulties were noted at one month post-chemoradiotherapy, and were experienced by a small number of patients. These patients continued to complain of voice difficulties at 3 and 6 months with regard to all physical, functional and emotional realms. Overall, patient-reported voice difficulties varied among all patients.

“Although patient numbers are small, this study identified discordance between observed swallowing function and patient-reported problems, which may have significant clinical implications for the management of patients with SCLC, as well as identify important issues for future research,” concluded the authors.

Related Articles

Resource Topics rightRail

  • Resource Topics
  • Partner Content
  • Breast Cancer
  • Acute Myeloid Leukemia
  • HER2-Positive Breast Cancer
  • Videos Breast Cancer
  • Follicular Lymphoma
Cutaneous T-Cell Lymphomas: Mycosis Fungoides and Sézary Syndrome
3 Keys to Success in the Oncology Care Model

Current Issue

ONCOLOGY Vol 33 No 11
Nov 21, 2019 Vol 33 No 11
Subscribe
Connect with Us
  • Column 1
    • Home
    • About Us
    • Contact Us
  • Column 2
    • Editorial Info
    • Editorial Board
  • Column 3
    • Advertising Info
    • Reprints
    • Advertising Terms
  • Column 4
    • Terms of Use
    • Privacy Policy
Modern Medicine Network
© UBM 2019, All rights reserved.
Reproduction in whole or in part is prohibited.

We've noticed that you're using an ad blocker

Our content is brought to you free of charge because of the support of our advertisers. To continue enjoying our content, please turn off your ad blocker.

It's off now Dismiss How do I disable my ad blocker?
❌

How to disable your ad blocker for our site:

Adblock / Adblock Plus
  • Click on the AdBlock / AdBlock Plus icon on the top right of your browser.
  • Click “Don’t run on pages on this domain.” OR “Enabled on this site.”
  • Close this help box and click "It's off now".
Firefox Tracking Prevention
  • If you are Private Browsing in Firefox, "Tracking Protection" may casue the adblock notice to show. It can be temporarily disabled by clicking the "shield" icon in the address bar.
  • Close this help box and click "It's off now".
Ghostery
  • Click the Ghostery icon on your browser.
  • In Ghostery versions < 6.0 click “Whitelist site.” in version 6.0 click “Trust site.”
  • Close this help box and click "It's off now".
uBlock / uBlock Origin
  • Click the uBlock / uBlock Origin icon on your browser.
  • Click the “power” button in the menu that appears to whitelist the current website
  • Close this help box and click "It's off now".