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Oncology and Hematology News and Journal Articles

Order of Gene Mutations May Affect Cancer Outcomes

New data indicates that the order in which people acquired certain somatic mutations influenced several clinical features of myeloproliferative neoplasms.

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Maintenance Sunitinib Improved PFS in Extensive-Stage SCLC

Cancer Network Staff
News | March 03, 2015 | Lung Cancer
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In a phase II study, the use of maintenance sunitinib improved progression-free survival among patients with untreated extensive-stage small-cell lung cancer.

Sentinel Lymph Node Biopsy Indicated in Thick Melanomas

Leah Lawrence
News | March 02, 2015 | Melanoma
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A single-institution study found that patients with melanomas of 4 mm thickness who had a negative sentinel lymph node biopsy had significantly prolonged survival.

Neutrophil-to-Lymphocyte Ratio Linked to mRCC Outcomes

Leah Lawrence
News | March 02, 2015 | ASCO 2015 Genitourinary Cancers Symposium, Genitourinary Cancers, Kidney Cancer, Renal Cell Carcinoma
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Metastatic renal cell carcinoma patients with an elevated neutrophil-to-lymphocyte ratio at baseline had inferior outcomes compared those with a low ratio.

Adjuvant Chemotherapy Improves Survival in Bladder Cancer

Leah Lawrence
News | March 02, 2015 | ASCO 2015 Genitourinary Cancers Symposium, Bladder Cancer, Genitourinary Cancers
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Patients with bladder cancer derived an overall survival benefit from the use of adjuvant chemotherapy compared with observation.

Two Clinical Factors May Predict PSA Response to Cabazitaxel

Anna Azvolinsky, PhD
News | March 02, 2015 | ASCO 2015 Genitourinary Cancers Symposium, Genitourinary Cancers, Prostate Cancer
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Two clinical factors may predict PSA response to cabazitaxel in men with metastatic castration-resistant prostate cancer.

Study Confirms 4Kscore Accurately Predicts High-Grade Prostate Cancer

Anna Azvolinsky, PhD
News | March 02, 2015 | ASCO 2015 Genitourinary Cancers Symposium, Genitourinary Cancers, Prostate Cancer
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The 4Kscore blood test has been shown to accurately detect the presence of high-grade prostate cancer, according to a study presented at ASCO GU.

High Cost, Minimal Benefit for Bevacizumab in Metastatic CRC

Leah Lawrence
News | March 02, 2015 | Colorectal Cancer, Gastrointestinal Cancer
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Bevacizumab as first-line therapy for metastatic CRC equated to an incremental cost-effectiveness ratio of more than half a million dollars per QALY.

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