Oncology and Hematology News and Journal Articles
Cancer Network presents exclusive coverage from the European Society for Medical Oncology (ESMO) World Congress on Gastrointestinal Cancer 2015. Below we bring you reports of the latest research, trials, scientific advances, and controversies that are changing the way gastrointestinal cancers are managed and treated.
A new study found that in patients treated for oropharyngeal cancer, the detection of HPV16 DNA via an oral rinse could be a sign of poor prognosis.
Treatment of CML with various tyrosine kinase inhibitors can induce changes in glomerular filtration rate over time and have other kidney-related effects.
Results of a study suggest that durable survival is possible in melanoma patients treated with MAPK inhibitors, and is perhaps similar to the survival observed with ipilimumab.
Whole-exome sequencing found that mutations of the NF1 gene are an important driver mutation in melanoma, and the third most frequently mutated gene.
A retrospective study was used to develop nomograms predictive of both metastasis-free and overall survival for patients with nonmetastatic osteosarcoma.
In this video, Dr. Paz-Ares discusses a phase III study that showed that nivolumab improved survival and response rates in previously treated patients with metastatic non-squamous non-small-cell lung cancer (NSCLC).
In this video, Steven I. Sherman, MD, discusses the final overall survival analysis of the EXAM study, a randomized, placebo-controlled phase III trial of cabozantinib in medullary thyroid carcinoma patients.
In this video, Dr. El-Khoueiry discusses results from a phase I/II study that suggest the PD-1 inhibitor nivolumab is safe and effective in advanced hepatocellular carcinoma.
In this video, Dr. Tap discusses a randomized phase Ib/II trial that found that adding olaratumab to doxorubicin dramatically improved survival in patients with advanced soft-tissue sarcoma.
This slide show features various images of cancers of the anal canal, including squamous cell carcinomas, anal melanomas, and so-called cloacogenic carcinomas.
This slide show highlights some of the top studies and news on cancer to come out of the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, held in Chicago.
This thyroid cancer slide show features pathology images of follicular carcinoma and Hurthle cell carcinoma at various magnifications.