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FDA Approves Camizestrant for ESR1-Mutated HR+/HER2– Advanced Breast Cancer
Novel Agent Earns FDA Breakthrough Therapy Designation for HPV+ Oropharyngeal Cancer
Debating Camizestrant, ctDNA Monitoring, and SERENA-6 in HR+ Breast Cancer
Saturated Fat Intake Linked to Greater Mortality in Nonmetastatic Prostate Cancer
Namodenoson Achieves Longer-Than-Anticipated Survival in Advanced HCC
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Speaking With “One Voice” for World Radiotherapy Awareness Day
Experts highlight the origins and significance of World Radiotherapy Awareness Day and discuss global access challenges surrounding modern radiation oncology.

How Mentorship and Peer Support Help Oncologists Avoid Burnout
Daniel C. McFarland, DO, and Xiomara Rocha-Cadman, MD, discussed why oncologist well-being depends on reflection, mentorship, and peer connection.

Exploring the Future of Radiopharmaceutical Therapy in Oncology
Experts discussed the rapidly expanding radiopharmaceutical paradigm and how to integrate such technology into real-world oncology practice.

How Will Successfully Targeting KRAS Change Pancreatic Cancer Treatment?
Frank McCormick, PhD, FRS, DSc (Hon), spoke about how targeting KRAS may eventually lead to the prevention of pancreatic cancer.

What Role Will Artificial Intelligence Play in Genitourinary Oncology?
Experts highlight how AI-based tools can assist with digital pathology, documentation, medical imaging, and other relevant areas in genitourinary oncology.

How to Treat Depression in Patients With Cancer: A Practical Framework
Daniel McFarland, DO, and Boris Kiselev, MD, discuss how oncologists can safely treat depression in patients with cancer, including medication choices.

Exploring CAR-T Updates in Pediatric Acute Lymphoblastic Leukemia
Two pharmacy specialists discuss real-world data and clinical trial findings on the use of CAR T-cell therapy for pediatric patients with hematologic cancers.

What Does Practical CAR T Cell Use Look Like in Multiple Myeloma Care?
Two hematologic oncology experts discuss operational and referral workflows, as well as barriers to access for CAR T-cell therapy in multiple myeloma.

Unraveling Immune Effector Therapy Advances Across Hematologic Oncology
Presenters at the 2026 National ICE-T Conference in Orlando, Florida, discuss the efficacy and safety of novel agents across hematologic disease states.

How Will Orca-T Impact the Hematologic Oncology Paradigm?
The approval of Orca-T represents a “big advance” that must be studied further, according to Wendy Stock, MD.
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Experts in breast cancer discussed final CAPItello-291 overall survival data and their implications for capivasertib plus fulvestrant.

Ropeginterferon alfa may play an important role in future combination strategies in essential thrombocythemia, said Ruben Mesa, MD, FACP.

Beth Sandy, CRNP, said she would like to see more data on management strategies for blepharitis, eye toxicities, and mucositis in patients with lung cancer.

Nevine Hanna, MD, MPH, FACRO, DABR, explained how AI can aggregate patient data to enhance multidisciplinary tumor board collaboration.

Blinded survival data from the phase 3 LIVERATION trial of namodenoson in advanced hepatocellular carcinoma appear longer than anticipated.

Matthew Matasar, MD, reflected on how quickly oncology has moved from skepticism to nimble adoption of AI, and what he expects from the field going forward.

Sandra Turner, MBBS, PhD, explained why September 7, radiotherapy’s first modern linac milestone, was chosen for World Radiotherapy Awareness Day.

According to Margarita Racsa, MD, MPH, patients coming in with AI-informed insights can be a double-edged sword for clinicians.

Patients with nonmetastatic prostate cancer in the highest quintile of postdiagnosis saturated fat consumption showed a 24% greater risk of all-cause mortality vs the lowest quintile.

Lisa Cassileth, MD, FACS, discussed her retrospective study showing that upsizing breast implants does not increase mastectomy flap necrosis risk.

Neil Iyengar, MD; Rebecca Shatsky, MD; and Carol Tweed, MD, discuss camizestrant and SERENA-6 ctDNA monitoring for ESR1-mutant HR+/HER2– breast cancer.

The FDA approval of ropeginterferon alfa-2b may lead to longer and better outcomes in essential thrombocythemia, according to Ruben Mesa, MD, FACP.

Matthew Matasar, MD, weighed the optimism and uncertainty surrounding AI’s expanding role in cancer drug discovery and clinical practice.

Radiopharmaceutical therapy currently falls somewhere between localized treatment and systemic therapy, according to Mallika Marar, MD, MBA.

The European Commission has approved T-DXd plus pertuzumab as first-line therapy for HER2-positive metastatic breast cancer based on DESTINY-Breast09.

Updated HERIZON-GEA-01 survival data show zanidatamab-based regimens outperformed trastuzumab/chemotherapy in first-line HER2-positive advanced GEA.

Matteo S. Carlino, MD, PhD, FRACP, discussed V940 plus pembrolizumab data, safety, and administration in resected melanoma.

The regulatory decision for JBS-003 is intended to help guide personalized radiation de-escalation in patients with HPV-positive oropharyngeal cancer.

Experts highlight the origins and significance of World Radiotherapy Awareness Day and discuss global access challenges surrounding modern radiation oncology.

Rethinking dose fractions and managing subclinical renal and marrow toxicity represent ongoing challenges associated with the use of radiopharmaceutical therapy.

Matthew Matasar, MD, discussed an AI-embedded deterioration index study, Epic’s patient-facing chatbot, and how AI is already absorbing routine documentation work.

AI is intended to assist physicians, giving them more time for interpersonal engagement with patients, according to Nevine Hanna, MD, MPH, FACRO, DABR.

Updated interim PYNNACLE trial data showed a 46% response rate with rezatapopt monotherapy in platinum-resistant/refractory ovarian cancer.

Tumor-informed ctDNA testing with the Signatera assay outperformed standard PET/CT imaging across B- and T-cell lymphoma subtypes.

Data from the phase 3 SENTRY trial support the supplemental new drug application for selinexor plus ruxolitinib in patients with myelofibrosis.

Matteo S. Carlino, MD, PhD, FRACP, discussed immune-related adverse event rates with V940 added to pembrolizumab.

ASCO’s updated breast cancer follow-up guideline replaces routine, one-size-fits-all surveillance with a 3-tier, risk-based model.

Final COMBI-I data show a survival advantage with spartalizumab plus dabrafenib/trametinib over dabrafenib/trametinib alone in BRAF V600-mutant melanoma.

Matthew Matasar, MD, outlined his wish list for AI in oncology, and detailed AI-bolstered tools already active across his 14-hospital health system.

Savolitinib/osimertinib significantly improved progression-free survival vs osimertinib alone as first-line treatment in the phase 3 SANOVO trial.

BioNTech has terminated a phase 2 trial of autogene cevumeran in ctDNA-positive, resected colorectal cancer after a DSMB found an overall survival imbalance.

Matteo S. Carlino, MD, PhD, FRACP, reviewed efficacy data for V940 plus pembrolizumab in resected melanoma.

Data from the phase 3 SURPASS ET trial supported the approval of ropeginterferon alfa-2b-njft for those with essential thrombocythemia.



































































