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Oncology and Hematology News and Journal Articles

The Promise of Chimeric Antigen Receptor T-Cell Therapy

In this review, we will describe the mechanism of action of CAR T cells, discuss outcomes of current clinical trials, and highlight emerging directions for this exciting approach to cancer treatment.

Recent Content

Patients with chronic myeloid leukemia with a history of prior malignancies generally fare as well as those without such a history, according to a new study.

A new study showed that a 24-gene signature can predict outcomes following postoperative radiotherapy in patients with prostate adenocarcinoma who underwent radical prostatectomy.

A 45-year-old man presents with symptoms of hypercalcemia. A neck mass is found, and a biopsy is performed. What is your diagnosis?

A 42-year-old man presents with a mass in his left leg, and a biopsy is performed. What is your diagnosis?

Adding seribantumab to paclitaxel failed to improved progression-free survival in unselected patients with platinum-resistant or -refractory ovarian cancer. Expression of heregulin and HER2, however, could identify a subset of patients that derive benefit from the therapy.

Use of tamoxifen and aromatase inhibitors therapy during and after breast cancer treatment were found to reduce the risk of contralateral breast cancer in a community healthcare setting.

In patients with HER2-positive breast cancer undergoing trastuzumab therapy, elevated troponin I or T before the treatment is associated with an increased risk of trastuzumab-related cardiac dysfunction.

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