Oncology and Hematology News and Journal Articles
Researchers at Kaiser Permanente were able to achieve complete histopathologic response in more than 40% of initially unresectable patients with pancreatic adenocarcinoma who underwent prolonged preoperative chemotherapy and were subsequently able to undergo surgical resection.
Major studies conducted to date looking at mammography screening and mortality have estimated that the number of women needed to be screened in order to prevent one breast cancer death ranged from 111 to 2,000, an almost 20-fold difference; however, the benefits of mammography may be more consistent than previously thought, according to a re-examination of these studies presented at the SABCS.
Surgical removal of primary breast cancer tumors had no benefit on overall survival in women who presented with metastatic breast cancer, according to the results of a study presented at SABCS.
Patients with HER2-positive breast cancer who achieved pathologic complete response had significantly improved event-free survival and overall survival over patients that did not, according to the trial results presented at SABCS.
A phase III trial of idelalisib plus rituximab in patients with previously treated chronic lymphocytic leukemia found that the combo improved progression-free and overall survival, according to results presented at the 2013 ASH meeting.
Patients with the rare and potentially deadly multicentric Castleman disease were able to achieve durable tumor and symptomatic response when assigned to treatment with the monoclonal antibody siltuximab, according to data presented at the 2013 ASH meeting.
The combination of lenalidomide plus dexamethasone demonstrated an improvement in both response rate and survival in newly diagnosed multiple myeloma patients not eligible for a stem cell transplant, according to data presented at the 2013 ASH meeting.
Adding dasatinib to standard antihormone therapy letrozole significantly improved the progression-free survival of women with hormone receptor–positive, HER2-negative metastatic breast cancer, according to the results of a small phase II
Major studies looking at breast cancer screening with mammography may have more consistent findings than previously though. Robert A.
A year-long exercise program reduced joint pain among breast cancer survivors taking aromatase inhibitors such as anastrozole, letrozole, and exemestane, according to the results of a study presented recently at the 2013 San Antonio Breas
In a 12-patient multiple myeloma pilot study, researchers demonstrated that anti-CD3 and anti-CD20 bispecific antibody (CD20Bi) activated both cellular and humoral anti-myeloma immunity that was detectable after patients received an autologous stem cell transplant.
In this interview we discuss advances in whole-genome analyses, as well as novel blood-based assays in development to help diagnose and follow cancer patients through their treatment.
As part of our coverage for the 2013 American Society of Hematology Annual Meeting and Exposition, we discuss some of the research that will be highlighted during this year’s meeting.
In this podcast, we discuss whether all male colorectal cancer patients over the age of 60 should be screened for prostate cancer.
At the 10th International Congress of the Society for Melanoma Research (SMR), we spoke with Dr. Georgina Long about current targeted approaches for the treatment of advanced-stage melanoma.