Jonathon B. Cohen, MD, MS

PI3K Inhibitors: Understanding Toxicity Mechanisms and Management

I. Brian Greenwell, MD
Andrew Ip, MD
Jonathon B. Cohen, MD, MS

Nov 15, 2017

Here, we briefly describe the clinical efficacy of PI3K inhibitors, then discuss the mechanisms and management of the more common unusual toxicities seen with these agents.

A Plethora of Novel Therapies—Which One to Choose?

Jonathon B. Cohen, MD, MS
Christopher R. Flowers, MD, MS

Jul 15, 2015

While the headliners for the 2015 ASCO Annual Meeting featured mainly immunologic approaches to cancer treatment, with agents such as nivolumab and ipilimumab, the new data in hematologic malignancies highlighted a large number of novel therapies, each of which appears promising.

Peripheral T-Cell Lymphoma: What’s the Role for Transplant?

Jonathon B. Cohen, MD, MS
Christopher R. Flowers, MD, MS

Sep 16, 2013

The number of recently approved agents and those under investigation is promising. However, there are currently no recommendations regarding the optimal timing for use of these agents, a reflection of the lack of data in this area and the need for prospective studies.