Triple Mutation More Deadly in Favorable-Risk AML
Researchers utilized a targeted next-generation sequencing (NGS) panel developed at Oregon Health & Science University to assess the clearance of mutations after therapy, clonal evolution at relapse, and combinations of mutations.
Risk of MGUS Progression in Multiple Myeloma Examined
Researchers looked to see how a patient's monoclonal gammopathy of undetermined significance status affects their risk for multiple myeloma.
Can HCC Be Caught Early Using ctDNA?
Researchers assessed patients with biliary tract cancer (BTC) who underwent ctDNA testing by means of a clinically available assay and analyzed samples using a 73-gene panel.
Management of Renal Carcinoma During Pregnancy
Laparoscopic treatment during pregnancy is becoming an option for more women.
Increased Survival in Metastatic Pancreatic Cancer
New Diagnostic Tool for Thyroid Cancer
New Hope for Advanced Sarcomas
Benefits of WBRT for Brain Metastases
In elderly patients with brain metastasis secondary to small cell lung cancer, whole brain radiation therapy was linked to a modest rise in survival.
Cervical Cancer During Pregnancy
Researchers looked at diagnosis, assessment, treatment, and prognosis of women diagnosed with cervical cancer while pregnant.
Fracture Risk in Men With Thyroid Cancer
Genomic Analysis of Anaplastic Thyroid Cancer
ASCO Highlights 2019
The 2019 American Society of Clinical Oncology (ASCO) Annual Meeting, which took place May 31–June 4 in Chicago, drew more than 32,000 oncology specialists from around the world.
Overview: FDA Approval of Olaparib Maintenance for BRCA-Mutated
The US Food and Drug Administration recently approved a new indication for olaparib for maintenance treatment in adult patients with germline or somatic BRCA-mutated advanced epithelial ovarian cancer.
New Treatment Option Available for Advanced Biliary Tract Cancers
A new trial investigated the efficacy of XELOX vs GEMOX as first-line therapy for advanced biliary tract cancers.
BLU-667 Shows Promise for Thyroid Cancer in Clinical Trials
Findings on the efficacy of the RET inhibitor BLU-667 in RET-altered medullary thyroid cancer and papillary thyroid cancer patients was presented at ASCO 2019.
Alarming Trend in Pediatric Thyroid Cancer Diagnoses Over Past 8 Years
Despite better detection, the incidence of pediatric thyroid cancer increased by 9.5% per year from 2006 to 2013 compared with 1.1% per year from 1973 to 2006.
Is Race Associated With Clinical Differences in Melanoma?
Study authors evaluated clinically relevant differences in nonwhite vs white pediatric patients with melanoma and atypical melanocytic neoplasms.
Report Provides Latest Incidence and Survival Statistics for Melanoma
The American Cancer Society's Cancer Facts & Figures 2019 report summarized the rate of melanoma over the past 30 years, mortality, and incidence based on sex and ethnicity.
FDA Approves Two New Indications and Dosage Form for Pembrolizumab
In this installment of Oncology Drug Updates, updates to FDA approvals for pembrolizumab in the treatment of lung cancer and RCC are highlighted.
Risk Factors for Recurrence in Papillary Thyroid Cancer Identified
Researchers found several risk factors for regional nodal recurrence in patients with papillary thyroid cancer, all of which can be easily evaluated in the clinical setting.
Can Vitamin D Serve as a Potential Biomarker for Thyroid Cancer?
Vitamin D deficiency may be a negative prognostic indicator for papillary thyroid cancer, according to the results of a recent retrospective study.
Review Touts Benefits of Immunotherapy for Non-Melanoma Skin Cancers
The authors discuss the potential use and limitations of immunotherapy among patients with squamous cell cancer, basal cell carcinoma, and other skin cancers.
Efficacy of One-Day Fractionated Photodynamic Therapy for Basal Cell Carcinoma
Researchers evaluated the response of patients with BCC to fractionated photodynamic therapy at 30 days after treatment.
Certain Factors Associated With Decreased QOL in Thyroid Cancer Survivors
A recent study in Surgery found that thyroid cancer survivors reported increased complications related to surgery and radioactive iodine ablation.
Thyroidectomy Still Popular Despite Less Aggressive Treatment Recommendations
A recent study evaluated the impact of recommendations encouraging less aggressive lobectomy for patients with small papillary thyroid cancers.
Precursor Immunotherapy to Prevent Squamous Cell Carcinoma
Researchers evaluated whether treatment with calcipotriol plus 5-fluorouracil aided in reducing the risk of squamous cell carcinoma.
Potential Role of the HPV Vaccine in Preventing Non-Melanoma Skin Cancers
The association between the presence of several viruses and non-melanoma skin cancer was investigated in a recent study.
Effect of Shorter Dose Interruption in Radioiodine-Refractory Differentiated Thyroid Cancer
Researchers evaluated the impact of dose interruption on survival for lenvatinib vs placebo in patients with progressive differentiated thyroid cancer.
Is Vitamin D Deficiency a Risk Factor for Thyroid Cancer?
A meta-analysis looked at the controversial link between decreased serum 25-hydroxyvitamin D levels and incidence of thyroid cancer.
Evidence on Nicotinamide for High-Risk Non-Melanoma Skin Cancers
A review published in Experimental Dermatology examined the safety and efficacy of nicotinamide in reducing non-melanoma skin cancers.