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Breast Cancer

70-Gene Signature Could Help Early-Stage Breast Cancer Patients Avoid Chemotherapy

Using a 70-gene signature test could identify many women with early-stage breast cancer considered to be at high clinical risk who do not actually need chemotherapy. Image © anyaivanova / Shutterstock.com.

Breast Cancer

Breast Cancer CTCs Can Flip Between HER2 Negativity and Positivity

Dave Levitan
News | September 20, 2016 | HER2-Positive Breast Cancer, Breast Cancer
By

Breast cancer tumors that are HER2-negative can spontaneously flip, with populations of circulating HER2-positive cells, suggesting treatment strategy.

Current Trends in the Management of Ductal Carcinoma In Situ

Tristen S. Park, MD
E. Shelley Hwang, MD, MPH
Review Article | September 15, 2016 | Oncology Journal, Breast Cancer
By and

This review will summarize the current trends in the diagnosis and management of DCIS and will highlight ongoing trials that are shaping future management of this entity.

Data on Ductal Carcinoma In Situ Encumbered by Opinion

V. Suzanne Klimberg, MD
September 15, 2016 | Oncology Journal, Breast Cancer
By

Despite the much higher risk of local recurrence with lumpectomy and radiation compared with mastectomy, multiple retrospective studies and prospective randomized trials have established that survival is the same; however, this may not be so for the individual patient, depending on the type of recurrence.

Laura Esserman and Ian Thompson Discuss Strategies for Screening and Treatment of Early-Stage Cancers, and How Clinicians Can Learn From Each Other’s Experiences

Laura J. Esserman, MD, MBA
Ian M. Thompson, Jr, MD
Q&A | September 15, 2016 | Oncology Journal, Breast Cancer, Prostate Cancer, Screening
By and

In this interview we review recent breast cancer screening guidelines from the ACS and USPSTF, and discuss the changing way that early-stage breast and prostate cancers are being treated.

Presence of DCIS, Younger Age Affect Breast Cancer Recurrence Risk

Anna Azvolinsky
News | September 09, 2016 | Breast Cancer
By

The presence of DCIS adjacent to invasive breast tumor and a younger age at diagnosis are associated with increased risk of ipsilateral breast tumor recurrence.

Telephone-Based Counseling Effective for Women at Risk of Hereditary Breast and Ovarian Cancer

Leah Lawrence
News | September 08, 2016 | Breast Cancer, Gynecologic Cancers, Ovarian Cancer
By

The use of telephone counseling for hereditary breast and ovarian cancer was noninferior to in-person counseling with no significant adverse effects on long-term outcomes.

Telephone Delivery of BRCA Genetic Counseling

Anita Y. Kinney, PhD, RN
September 08, 2016 | Breast Cancer, Gynecologic Cancers, Ovarian Cancer
By

A recent study found that use of telephone-based genetic counseling for women at risk of hereditary breast and ovarian cancers was noninferior to in-person counseling, with no significant adverse effects on long-term outcomes.

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