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Five New Risk Loci Identified for Gliomas
A new genetic analysis found five new genetic variants that raise the risk for gliomas. One of the five was associated with a sharply increased risk for glioblastoma.
Basket Trial Finds New Tumor Types That Respond to BRAF Inhibition
A basket trial of patients with various nonmelanoma BRAF-mutated cancers has shown that additional tumor types may also be responsive to vemurafenib.
PIK3CA Mutations May Predict Resistance in HER2-Positive Breast Cancer
Breast cancer patients with PIK3CA gene mutations may not benefit from dual anti-HER2 inhibition, according to a new study in The Oncologist.
Gene Expression May Help Predict Sentinel Lymph Node Positivity in Melanoma Patients
By exploring gene expression variables in addition to clinicopathologic variables, researchers were able to better predict which melanoma patients would have sentinel lymph node biopsy positivity.
DNMT3A Mutation Related to Poor-Risk AML
Patients with acute myeloid leukemia who had a DNMT3A mutation had poorer disease prognosis, according to an analysis of patients aged 60 years or younger.
African American NSCLC Patients Have Similar Rates of Driver Mutations
Genotyping of African Americans suggest that with regard to somatic driver mutations in non-small-cell lung cancer (NSCLC), black patients do not significantly differ from white patients, according to a new study.
The IBD-Cancer Link: 3 Key Questions
There is a lot of new information about the link between various malignancies and inflammatory bowel disease. Here: answers to 3 key questions.
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