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Colorectal Cancer

Colorectal Cancer

Mortality from colorectal cancer has decreased since 1970 in young black patients aged 20 to 54, but has increased in white patients since 1995 in those aged 30 to 39 years and since 2005 in those aged 40 to 54 years after decades of decreasing.

The FDA has granted accelerated approval to nivolumab for use in adult and adolescent patients with MSI-H or dMMR metastatic colorectal cancer.

Two studies on Lynch syndrome highlight cancer screening and surveillance opportunities.

Overweight and obesity in adolescence were associated with an increased risk for colon cancer later in life among both men and women, according to the results of a recent study.

Here we review the evidence for use of biologic agents in the second-line setting and beyond. We also discuss off-label indications for biologics in selected patient populations, as well as biologics currently under development.

Holocaust survivors have a small but consistent increase in the risk of developing cancer, in particular colorectal and lung cancers.

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