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Colorectal Cancer

Colorectal Cancer

Dual HER2 blockade with trastuzumab and lapatinib yielded good response rates in HER2-amplified, RAS wild type, treatment-refractory metastatic colorectal cancer patients, according to results of the HERACLES study.

Aspirin had a greater effect on colorectal cancer survival in patients with low-level CD274 (PD-L1) expression in their tumors, according to the results of a study.

Recent improvements in our understanding of the biology of colorectal cancer have led to the identification of several important prognostic and predictive markers of disease-associated risk and treatment response for the individual patient.

Adjuvant chemotherapy is underutilized in elderly patients with stage III colon cancer, despite improved long-term survival after treatment.

In this interview we discuss the role of genetic testing in patients with colon cancer.

No difference in time to recurrence, recurrence-free survival, or overall survival were noted for patients with rectal cancer who underwent one of three different preoperative radiotherapy regimens.

Completing a course of preoperative radiotherapy prior to undergoing surgical resection for rectal cancer was associated with improved survival compared with patients who had an incomplete course of radiotherapy.


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