REVIEW ARTICLE Kasmintan Schrader, et al; ONCOLOGY Vol. 26 No. 5 In this article, we use a case-based approach to focus on the hereditary aspects of the most common GI cancers, including pancreatic, gastric, and colon cancer.
REVIEW ARTICLE David L. Bartlett, Edward Chu;ONCOLOGY Vol. 26 No. 3 Despite advances in targeted biologic agents, the impact of new regimens in mCRC therapy has been modest. This article reviews the main issues that must be considered from the surgical and medical oncology perspectives.
REVIEW ARTICLE Al B. Benson, III, Jose G. Guillem, Bruce D. Minsky;ONCOLOGY Vol. 25 No. 14 Treatment for patients with locally advanced, resectable rectal cancer has clearly evolved, with significant refinements in preoperative assessment, surgical technique, and use of preoperative CMT.
REVIEW ARTICLE Lyen C. Huang, George A. Poultsides, Jeffrey A. Norton; ONCOLOGY Vol. 25 No. 9 This article reviews the surgical management of gastrointestinal neuroendocrine tumors, including the preoperative control of hormonal symptoms, extent of resection required, postoperative outcomes, and differing management strategies.
Studies of IGF-1R inhibitors in gastrointestinal cancers are currently ongoing in pancreatic, gastroesophageal, hepatocellular, and colorectal cancers. A critical analysis of prior work in this field and a rational strategy for maximizing success on the basis of biomarker use are necessary. • Targeting IGF-1R: at a Crossroad • The IGF-1R Pathway as a Therapeutic Target
Several years ago, a 44-year-old nonsmoking Taiwanese immigrant to the United States sought medical attention for the skin eruption depicted. This disorder had been present since he was 25; he notes an involuntary 35-pound weight loss and increasing fatigue. What is the patient’s skin disease?
A 74-year-old, previously healthy, nonsmoking Caucasian male presented with a 4-month history of an asymptomatic “lump” in the navel. Biopsy of the umbilical nodule revealed adenocarcinoma. What eponym is attached to the umbilical lesion?
A large study shows that middle-age men engaged in lots of cardiovascular exercise have a reduced risk of developing and dying from lung and colorectal cancer. More »
Adding the VEGF inhibitor axitinib to first-line treatment of FOLFOX-6 for metastatic colorectal cancer failed to improve progression-free and overall survival. More »
Women diagnosed with endometrial cancer at age 50 or younger had a fourfold increased risk for a subsequent colorectal cancer diagnosis, according to a historical cohort study published recently in the Journal of Clinical Oncology. More »
Patients with stage III colon cancer who have a history of smoking are more likely to have worse outcomes, according to a large, randomized phase III trial result. More »
Using blood samples of pancreatic cancer and chronic pancreatitis patients, researchers in Japan have developed a metabolomics-based test that may be an easy and noninvasive way to detect pancreatic cancer. More »
In this interview, Dr. David Ahlquist, gastroenterologist and professor of medicine at the Mayo Clinic in Rochester in Minnesota, discusses early detection methods of colorectal cancer, touching on sigmoidoscopy, colonoscopies, fecal blood testing, and in particular, stool DNA screening.
This article reviews the surgical management of gastrointestinal neuroendocrine tumors, including the preoperative control of hormonal symptoms, extent of resection required, postoperative outcomes, and differing management strategies.
In the future, as local-regional therapy improves or as novel anti-tumor medications become available, this modality may be able to be made available to patients whose disease does not meet the current Milan criteria while still providing them with acceptable long-term outcomes.
Studies of IGF-1R inhibitors in gastrointestinal cancers are currently ongoing in pancreatic, gastroesophageal, hepatocellular, and colorectal cancers. A critical analysis of prior work in this field and a rational strategy for maximizing success on the basis of biomarker use are necessary.
Less is known about the effects of sorafenib in patients with decompensated liver disease, or of sorafenib in combination with local therapy or in a transplant setting. Prospective trials are lacking in these areas.
A 47-year-old male with complaints of chronic abdominal pain and episodes of flushing presents for evaluation. What is your diagnosis?
Several years ago, a 44-year-old nonsmoking Taiwanese immigrant to the United States sought medical attention for the skin eruption depicted. This disorder had been present since he was 25; he notes an involuntary 35-pound weight loss and increasing fatigue. What is the patient’s skin disease?
A 74-year-old, previously healthy, nonsmoking Caucasian male presented with a 4-month history of an asymptomatic “lump” in the navel. Biopsy of the umbilical nodule revealed adenocarcinoma. What eponym is attached to the umbilical lesion?
In this interview, Dr. David Ahlquist, gastroenterologist and professor of medicine at the Mayo Clinic in Rochester in Minnesota, discusses early detection methods of colorectal cancer, touching on sigmoidoscopy, colonoscopies, fecal blood testing, and in particular, stool DNA screening.
