Sequencing of Agents for Castration-Resistant Prostate Cancer

In this review we will outline an approach to sequencing new therapies for metastatic castration-resistant prostate cancer (CRPC), with particular attention paid to the biology of CRPC.

Genitourinary Cancers

Temsirolimus Fails in Metastatic RCC Trials

Leah Lawrence

News | December 08, 2013 | Renal Cell Carcinoma, Genitourinary Cancers, Kidney Cancer

By Leah Lawrence

In two phase III trials, the mTOR inhibitor temsirolimus failed to improved progression-free survival outcomes for patients with metastatic renal cell carcinoma compared with other therapeutic options.

Protein in Prostate Biopsy May Signal Higher Risk of Cancer

Anna Azvolinsky, PhD

News | December 06, 2013 | Genitourinary Cancers, Prostate Cancer

By Anna Azvolinsky, PhD

A new study shows that men who have a specific protein marker present in their prostate biopsy may benefit from close follow-up and additional biopsies as they may be at increased risk of developing cancer.

In Metastatic RCC, 10% Tumor Shrinkage Valid Indicator of VEGF Response

Leah Lawrence

News | December 05, 2013 | Renal Cell Carcinoma, Genitourinary Cancers, Kidney Cancer

By Leah Lawrence

Tumor shrinkage is a valid indicator of response to VEGF inhibition among patients with metastatic renal cell carcinoma when evaluated by a single radiologist observer.

Anxiety Linked to Prostate Biopsies

Anna Azvolinsky, PhD

News | November 29, 2013 | Prostate Cancer, Genitourinary Cancers

By Anna Azvolinsky, PhD

The results of a recently published study on the psychological impact of prostate cancer biopsies show that men who have post-biopsy symptoms have increased anxiety, even if they received a negative diagnosis.

Circling Back: PSA Screening for Colorectal Cancer Patients

Ayal A. Aizer, MD, MHS

November 24, 2013 | Oncology Journal, Colorectal Cancer, Gastrointestinal Cancer, Genitourinary Cancers, PSA Screening, Prostate Cancer, Screening

By Ayal A. Aizer, MD, MHS

In this podcast, we discuss whether all male colorectal cancer patients over the age of 60 should be screened for prostate cancer.

No Significant PFS Benefit With Axitinib in First-Line Metastatic RCC

Leah Lawrence

News | November 19, 2013 | Renal Cell Carcinoma, Genitourinary Cancers

By Leah Lawrence

The second generation VEGFR inhibitor axitinib did not significantly improve progression-free survival in first-line treatment of patients with metastatic renal cell carcinoma compared with patients treated with sorafenib.

Radiofrequency Ablation Safe, Effective for Small Renal Tumors

Leah Lawrence

News | November 16, 2013 | Renal Cell Carcinoma, Genitourinary Cancers

By Leah Lawrence

Image-guided radiofrequency ablation may be an effective alternative treatment for small renal cell carcinoma tumors, according to the results of a recent study.

Pages

Videos
Podcasts

Recurrence and Relapse in Testicular Cancer
Bruce Roth, MD
August 09, 2013 | Testicular Cancer, Genitourinary Cancers
By Bruce Roth, MD
Dr. Bruce Roth, Siteman Cancer Center, spoke at the 2013 ASCO meeting about topics in seminoma. Here he discusses recurrence, relapse, and seminomatous vs nonseminomatous testicular cancer.
Epidemiology of Seminoma
Bruce Roth, MD
August 09, 2013 | Testicular Cancer, Genitourinary Cancers
By Bruce Roth, MD
Dr. Bruce Roth, Professor of Oncology in the Division of Medicine at Siteman Cancer Center, Washington University at St. Louis, spoke at the 2013 ASCO meeting about topics in seminoma. Here he discusses the epidemiology of seminoma.
Surveillance for Stage I Seminoma: Part II
Bruce Roth, MD
News | August 09, 2013 | Testicular Cancer, Genitourinary Cancers
By Bruce Roth, MD
Dr. Bruce Roth discusses the large Danish study reported at ASCO (abstract 4502) that showed surveillance alone is sufficient after orchiectomy for stage I seminoma, focusing on its impact on post-surgery radiation therapy in this setting.
Surveillance for Stage I Seminoma: Part I
Bruce Roth, MD
August 09, 2013 | Testicular Cancer, Genitourinary Cancers
By Bruce Roth, MD
Dr. Bruce Roth discusses the large Danish study reported at ASCO (abstract 4502) that showed surveillance alone is sufficient after orchiectomy for stage I seminoma.