RESEARCH REPORT Dave Levitan Expression of the beta-3 tubulin (ß3T) isoform was a negative prognostic factor in non–small-cell lung cancer (NSCLC) patients, but did not predict treatment response for either paclitaxel or tubulin-inhibiting chemotherapy with ixabepilone.
REVIEW ARTICLE This review will describe the well-known use of VEGF antibodies; the current uses of EGFR and ALK tyrosine kinase inhibitors; newer agents being used against MET, FGFR, and other intracellular targets; insights regarding the field of immunotherapy in lung cancer; and finally, newer developments in chemotherapy.
A 49-year-old woman insidiously developed spotty depigmentation of the chest along with thickened and bound-down skin of the upper torso. In addition, all of her fingers were swollen and her facial skin became so tight that she had difficulty smiling. What is her diagnosis?
A 71-year-old man with a smoking history of more than 100 pack-years developed non–small-cell carcinoma of the lung. During his an infusion of vancomycin he developed flushing, followed by widespread fixed erythema, muscular spasms in the back, and transient but severe hypotension. Can he ever receive vancomycin again?
In this interview, ahead of the AACR annual meeting, we speak with Dr. Julie Brahmer, of Johns Hopkins School of Medicine, who is giving a presentation on immunotherapy in lung cancer, and is one of the clinical investigators of the extensive phase I trial of the anti–PD-1 antibody nivolumab.
Five Steps to Improving Patient Access Judy Capko, May 21, 2013 Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.