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Melanoma

Isolated Limb Perfusion for Stage III Melanoma: Does It Still Have a Role in the Present Era of Effective Systemic Therapy?

Effective systemic therapy for the treatment of stage III melanoma has emerged. Whether this influences treatment choice in stage III melanoma patients with in-transit metastases is the subject of this review.

Melanoma

The MEK inhibitor binimetinib improved progression-free survival compared with dacarbazine in patients with NRAS-mutant melanoma, according to the results of the NEMO trial.

Although long-term melanoma survivors were more likely to report healthier levels of ultraviolet radiation exposure and sun protection behaviors than controls, some still reported indoor tanning or intentionally seeking sun to tan.

The identification of ugly duckling nevi using a whole-body skin examination for intrapatient comparative analysis improves accuracy of melanoma detection.

The immunotherapy pembrolizumab was active in patients with advanced mucosal melanoma enrolled in a series of the KEYNOTE clinical trials, according to data presented at the European Cancer Congress 2017.

A multicenter study showed that an occurrence of posttransplant skin cancer was common among a group of organ transplant recipients.

Participation in a training program increased levels of self-confidence for both patients and their partners in performing skin self-examinations to detect melanoma.

Effective systemic therapy for the treatment of stage III melanoma has emerged. Whether this influences treatment choice in stage III melanoma patients with in-transit metastases is the subject of this review.

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