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Ovarian Cancer

The Emerging Role of HE4 in the Evaluation of Epithelial Ovarian and Endometrial Carcinomas

This article discusses the discovery and biologic significance of HE4 and evaluates available evidence regarding the utility of HE4 as a biomarker for ovarian and endometrial cancer.

Ovarian Cancer

Guidelines Recommend Against Routine Pelvic Exams

Janet Colwell
News | July 07, 2014 | Practice & Policy, Gynecologic Cancers, Ovarian Cancer
By

A new clinical practice guideline from the American College of Physicians recommends against conducting routine pelvic exams in average-risk, asymptomatic women.

Guide Answers Questions About Sex After Cancer Treatment

Janet Colwell
News | June 20, 2014 | Oncology Nursing, Gynecologic Cancers, Ovarian Cancer
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A new guide developed by nurses and patients with gynecologic cancer offers a much-needed practical resource for women struggling to understand the impact of cancer treatment on their sexual health.

SGO Recommends Genetic Testing for Endometrial and Ovarian Cancer Patients

Janet Colwell
News | March 28, 2014 | Practice & Policy, Endometrial Cancer, Gynecologic Cancers, Ovarian Cancer
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The Society of Gynecologic Oncology (SGO) recently issued two new clinical practice statements recommending genetic testing for all women with endometrial and ovarian cancers, regardless of family history.

Healthy Weight Trims Ovarian Cancer Risk

Mark L. Fuerst
News | March 17, 2014 | Ovarian Cancer
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Being overweight increases a woman’s risk of ovarian cancer, according to a new comprehensive report. The finding offers a way to reduce the risk.

Vitamin C Boosts Effects of Chemotherapy and Lessens Toxicity

Anna Azvolinsky, PhD
News | February 06, 2014 | Ovarian Cancer, Gynecologic Cancers
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A new study found that high concentrations of vitamin C increased the effectiveness of chemotherapy in an ovarian cancer mouse model. A high-dose delivery of the vitamin also resulted in lesser toxicity from chemotherapy in cancer patients.

Oral Contraceptive Use Lowers Ovarian Cancer Risk in BRCA1/2 Carriers

Leah Lawrence
November 21, 2013 | Breast Cancer, Ovarian Cancer
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The use of oral contraceptives in women with BRCA1/2 mutations was associated with a reduced risk of ovarian cancer.

New Targets for Triple-Negative Breast Cancer

Christina I. Herold, MD
Carey K. Anders, MD
Review Article | September 15, 2013 | Oncology Journal, Breast Cancer, Ovarian Cancer, Triple-Negative Breast Cancer
By and

With regard to potential research strategies relevant to the treatment of triple-negative breast cancer/basal-like breast cancer, potential targets include PTEN, INPP4B, PIK3CA, KRAS, BRAF, EGFR, FGFR1, FGFR2, IGFR1, KIT, MET, PDGFRA, and the HIF1-α/ARNT pathway. Many of these will be discussed further in this review article.

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