RESEARCH REPORT Leah Lawrence The addition of adjuvant chemotherapy using doxorubicin, ifosfamide, and cisplatin, to pelvic radiation therapy for the treatment of uterine sarcomas increased 3-year disease-free survival in a group of women with localized disease, but also resulted in two toxic deaths among the study group.
RESEARCH REPORT Leah Lawrence Decreasing the time between cycles of standard chemotherapy for Ewing’s sarcoma from 3 weeks to 2 weeks increased event-free survival without an associated increase in toxicity, according to the results of a Children’s Oncology Group report.
REVIEW ARTICLE Zachary Kon, Linda Martin;ONCOLOGY Vol. 25 No. 12 This article provides an extensive review of patient selection criteria and surgical approaches, as well as of controversies regarding resection for metastatic sarcoma.
TEST YOUR IMAGE IQ Cesar Moran, MD An 18-year-old man presented with symptoms of pain in his right leg just above the knee. The patient does not have any history of trauma or any other medical condition. Radiographic examination shows the presence of a destructive mass involving the right femur. What is your diagnosis?
We describe areas where major inroads were initially achieved by targeting angiogenesis and by unraveling
pathways in the heterogeneous tumors of mesenchymal origin—spurred by the identification of c-Kit–activating
mutations in GIST and the regressions that ensued when tumors harboring these mutations were exposed to the
tyrosine kinase inhibitor imatinib (Gleevec).
• Improving Harmonious Precision • Targeted Therapy for Cancer: Asking the Right Questions
This case shows the importance of searching for antineural antibodies in oncologic patients with new neurologic deficits, and of having a judicious workup for occult malignancies in patients with known antineural antibodies.
• Unraveling the Mystery of a Supraclavicular Mass
Our case illustrates the fact that MDS-associated GS can be treated palliatively with radiation and hypomethylating agents in an appropriate setting. With the growing geriatric patient population, effective treatment options are needed in this disease.
A 45-year-old man presented with swelling of the parotid gland. At physical examination a mass at the level of the parotid gland was found. Surgical resection of the mass was performed. What is your diagnosis?
Five Steps to Improving Patient Access Judy Capko, May 21, 2013 Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.