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Oncology and Hematology News and Journal Articles

The Promise of Chimeric Antigen Receptor T-Cell Therapy

In this review, we will describe the mechanism of action of CAR T cells, discuss outcomes of current clinical trials, and highlight emerging directions for this exciting approach to cancer treatment.

Recent Content

Adding seribantumab to paclitaxel failed to improved progression-free survival in unselected patients with platinum-resistant or -refractory ovarian cancer. Expression of heregulin and HER2, however, could identify a subset of patients that derive benefit from the therapy.

Use of tamoxifen and aromatase inhibitors therapy during and after breast cancer treatment were found to reduce the risk of contralateral breast cancer in a community healthcare setting.

In patients with HER2-positive breast cancer undergoing trastuzumab therapy, elevated troponin I or T before the treatment is associated with an increased risk of trastuzumab-related cardiac dysfunction.

This Medical News Minute outlines efforts by a number of advocacy groups and medical associations urging the CMS to abandon proposed reimbursement cuts to low-dose CT screening for lung cancer.

This Medical News Minute examines a recent report that found that chronic infection with hepatitis B or C virus was associated with an increased risk for lymphoma among HIV patients on antiretroviral therapy.

A phase II study of sonepcizumab has failed to meet its primary progression-free survival endpoint in patients with metastatic renal cell carcinoma.

A study presented last month at ASTRO found that a boost of radiation therapy following lumpectomy in DCIS patients resulted in reduced rates of local recurrence.

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