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Depression, Impaired Executive Function Shortens Survival in Glioblastoma
Depressive symptoms and impaired executive functioning, both common in patients with glioblastoma, are independently associated with shorter overall survival.
Core Set of Symptoms Highlighted for Brain Tumor Patients
A core set of symptoms are common across brain tumor patients and underscore the complexity of brain tumors and their management.
Genomic Analysis Will Reshape Low-Grade Glioma Classification, Treatment
New research suggests that characterizing low-grade gliomas according to molecular markers may be a more useful approach in order to guide treatment decisions.
Rindopepimut Vaccine With Bevacizumab Ups Survival in Recurrent Glioblastoma
The immunotherapeutic rindopepimut with bevacizumab yielded a significant survival improvement in relapsed glioblastoma patients with a EGFRvIII mutation.
Polio-Rhinovirus Conjugate Shows Promise in Early Recurrent Glioblastoma Trial
A phase I trial of an oncolytic polio/rhinovirus vaccine was safe and showed promising efficacy in patients with recurrent glioblastoma.
Electric Field Treatment Offers New Standard for Newly Diagnosed Glioblastoma
Treating newly diagnosed glioblastoma with “tumor treating fields” is a safe and effective therapeutic option, according to a new trial.
PCV Added to Radiation Therapy Improves Survival Most in Low-Grade Glioma Subtypes
The addition of procarbazine, CCNU, and vincristine to RT in patients with low-grade glioma prolongs progression-free and overall survival vs RT alone.
Bevacizumab/Lomustine Combo Shows Promise in Recurrent Glioblastoma
A combination of bevacizumab and lomustine showed promise in a randomized phase II trial of patients with recurrent glioblastoma, according to study results.
Quality-of-Life Issues Important in Neuro-Oncologic Treatment
As part of our Society of Neuro-Oncology annual meeting coverage, we discuss quality of life issues and neurologic rehabilitation in patients with neuro-oncologic diseases.