ADA Inhibitors: Recent Developments and Future Directions in Low-Grade Lymphoma
June 1st 2000Pentostatin (Nipent) is a nucleoside analog that inhibits the activity of the enzyme adenosine deaminase. Inhibition of adenosine deaminase blocks the deamination of adenosine to inosine and deoxyadenosine to deoxyinosine in the purine