A panel of experts review the historically available treatment decision-making tools for patients with colorectal cancer and discuss the current and future use of minimal residual disease (MRD) and circulating tumor DNA (ctDNA) testing as it relates to key clinical trial data.
EP. 1: Patient Scenario: A 64-Year-Old Man with Stage II Colon CancerFebruary 10th 2023
Tanios S. Bekaii-Saab, MD, presents a patient scenario of a 64-year-old man with stage 2 (pT3N0) colon cancer to the panel for discussion.
EP. 2: Considering a Patient with Colorectal Cancer for Adjuvant ChemotherapyFebruary 10th 2023
Aparna Parikh, MD, MS, details when she would recommend adjuvant chemotherapy to patients with similar presentations of colorectal cancer.
EP. 3: Over- and Under-Treatment of Stage II and III Colorectal Cancer in the Adjuvant SettingFebruary 16th 2023
Stacey A. Cohen, MD, and Daniel H. Ahn, DO, describe the challenges of deciding which patients with colorectal cancer should receive adjuvant therapy, and the risk of over- and under-treatment in later stages.
EP. 4: Monitoring a Patient with Colorectal Cancer After Adjuvant TherapyFebruary 16th 2023
Dr Stacey A. Cohen discusses how she typically monitors patients with stage II and III colorectal cancer during and after adjuvant therapy.
EP. 5: Testing for Minimal Residual Disease (MRD) in Patients with Colorectal CancerFebruary 24th 2023
Dr Aparna Parikh explains minimal residual disease (MRD) in colorectal cancer and the logistical challenges of MRD testing.
EP. 6: Emerging Biomarkers for Assessing Therapy Response in Colorectal CancerFebruary 24th 2023
The panel discusses other emerging biomarkers for monitoring patient response to therapy for colorectal cancer.
EP. 7: Circulating Tumor DNA and its Use in Colorectal Cancer Treatment Decision-MakingMarch 3rd 2023
Aparna Parikh, MD, MS, defines circulating tumor DNA (ctDNA) and the use of ctDNA assays in colorectal cancer.
EP. 9: Utilizing ctDNA Assays in Colorectal Cancer for Treatment and Monitoring of Patients with Solid TumorsMarch 10th 2023
The panel reviews the different settings in colorectal cancer where ctDNA is being investigated as a tool for treatment and monitoring.
EP. 10: Key Clinical Trial Data on ctDNA Assays in Colorectal CancerMarch 10th 2023
Stacey A. Cohen, MD, and Aparna Parikh, MD, MS, review the design and outcomes of key clinical trials exploring the use of ctDNA assays in colorectal cancer.