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A phase 1/2 study found that using azacitidine, venetoclax, and gilteritinib for patients with FLT3-mutated acute myeloid leukemia yielded high rates of complete response and complete response with incomplete hematologic recovery.
Azacitidine Combo Shows High Response Rates in FLT3-Mutated AML

February 26th 2024

A phase 1/2 study found that using azacitidine, venetoclax, and gilteritinib for patients with FLT3-mutated acute myeloid leukemia yielded high rates of complete response and complete response with incomplete hematologic recovery.

Findings from the phase 1/2 TRANSCEND CLL 004 trial support lisocabtagene maraleucel as a potential new treatment option for relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Liso-cel Yields Enduring Responses in R/R Chronic Lymphocytic Leukemia

February 25th 2024

Findings from a retrospective study demonstrate the feasibility of using brexucabtagene autoleucel to treat patients with relapsed/refractory B-cell acute lymphoblastic leukemia with central nervous system involvement.
Brexu-cel Clears CNS Disease in R/R B-Cell Acute Lymphoblastic Leukemia

February 22nd 2024

Measurable residual disease–guided ibrutinib plus venetoclax in chronic lymphocytic leukemia appears to be particularly beneficial in patients with unmutated IGHV and specific genetic abnormalities.
MRD-Directed Ibrutinib Combo Improves PFS in Chronic Lymphocytic Leukemia

February 17th 2024

Pediatric-Inspired Asparaginase Regimens for Patients With Acute Lymphocytic Leukemia
Pediatric-Inspired Asparaginase Regimens for Patients With Acute Lymphocytic Leukemia

February 14th 2024

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