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FDA Approves Third Pegfilgrastim Biosimilar, LA-EP2006

The agency based its decision on analytical, preclinical and clinical research, including data from a pivotal three-way pharmacokinetics (PK) and pharmacodynamics (PD) study, called LA-EP06-104.

Recent Content

Dasatinib Yields Superior Results Compared to Imatinib in Pediatric Patients with ALL

January 22, 2020
  • Hannah Slater

Combined with intensive chemotherapy, the next-generation inhibitor provided excellent results in pediatric patients with Philadelphia chromosome-positive ALL, leading to changes in how this population is treated.

Genetic Risk Score Associated with Patient Age at Prostate Cancer Diagnosis

January 22, 2020
  • Hannah Slater

This research found that combining family history and a genetic risk score could better stratify inherited risk for developing prostate cancer.

Atezolizumab in Combination with Bevacizumab May Be Effective for Patients with HCC

January 22, 2020
  • Hannah Slater

High-quality patient reported outcomes were observed, suggesting benefits in key aspects of the patient experience with this combination treatment.

Older Breast Cancer Survivors May Experience Higher Symptom Burden

January 22, 2020
  • Hannah Slater

These data indicate the need for surveillance and opportunities for intervention in this population.

High BMI Associated with Improved OS Following Atezolizumab in Advanced NSCLC Treatment

January 21, 2020
  • Hannah Slater

A recent study indicated that baseline BMI should be considered as a stratification factor in future immune checkpoint inhibitor therapy trials.

Activation of Apelin Signaling Decreases VEGF Inhibitor Efficacy in Ovarian Cancer Treatment

January 21, 2020
  • Matthew Fowler

A recent study suggested the activation of apelin/APJ signaling decreased efficacy in VEGF treatment, while bevacizumab decreased disease-free survival rates with increased expression of apelin in patients of ovarian cancer.

FDA Grants Priority Review to Belantamab Mafodotin for Relapsed/Refractory Myeloma

January 21, 2020
  • Kristie L. Kahl

The agency granted the immunoconjugate targeting B-cell maturation antigen priority review to belantamab mafodotin for the treatment of heavily pre-treated patients with relapsed or refractory multiple myeloma.

FDA Grants Fast Track Designation to Oncoprex Combination for NSCLC

January 21, 2020
  • Kristie L. Kahl

Oncoprex in combination with osimertinib received fast track designation from the FDA to treat patients with non-small cell lung cancer.

Early-Onset Gastric Cancer Suggested to be Genetically and Clinically Distinct

January 20, 2020
  • Hannah Slater

Incidence of early-onset gastric cancer has steadily increased in the US, now comprising >30% of new gastric cancer cases today, causing researchers to try and discover what makes this disease type unique.

Online and Digital Videos Can Play Key Role in Cancer Education

January 20, 2020
  • Kevin Wright

Research shows that digital videos led to increased knowledge and interventions, but access for vulnerable populations must be improved.

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Cutaneous T-Cell Lymphomas: Mycosis Fungoides and Sézary Syndrome
3 Keys to Success in the Oncology Care Model

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ONCOLOCGY
Jan 22, 2020 Vol 34 No 1
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