Genitourinary Cancers

The FDA  approved pembrolizumab (Keytruda) for the treatment of patients with Bacillus Calmette-Guerin (BCG)-unresponsive, high-risk, non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumors who are ineligible for or chose to not undergo cystectomy.

Results of this phase III trial could change the current standard of care for treating nonseminomatous or combined germ cell tumors of the testis.

The study found that patients who were randomized to receive avelumab and best supportive care lived significantly longer than those who only received best supportive care.