
Ethan B. Ludmir, MD, discussed neoadjuvant radiation, advanced treatment techniques, the HYPERION CCA trial, and lirafugratinib in cholangiocarcinoma.
A 54-year-old woman, previously in excellent health, noted the insidious development of abundant, thin, and softly textured, nonpigmented hair on her ears and nose. A detailed review of systems was entirely negative, and both a complete blood count and automated routine biochemistry panel were normal. Gynecologic examination, including a pap smear, was normal one year prior to presentation. The patient was a lifelong nonsmoker and nondrinker. Family history was negative for cancer.
From what specific disorder does she suffer?





![“[W]e should strive to increase the [number] of patients…who enjoy long-term disease-free survival and possibly cure,” said Meletios Dimopoulos, MD.](https://cdn.sanity.io/images/0vv8moc6/cancernetwork/c7abebf9344f9b1be9aee80d9879d139c1655bcc-1200x1197.jpg?w=350&fit=crop&auto=format)
