Persistent, Intensely Painful Ulceration of the Contralateral Breast

A 71-year-old woman was receiving a multi-agent chemotherapeutic regimen following a lumpectomy for breast cancer. After the second round of treatment, she presented for medical care due to persistent, intensely painful ulceration of the contralateral breast. The process depicted began as scattered erythematous papules, which became coalescent and then eroded over a seven-day period.