
“When we give the most effective therapy at the time of new diagnosis, we get the most value out of the effort and time that we and our patients are spending,” said Neeraj Agarwal, MD, FASCO.
A 21-year-old woman developed the photosensitive facial rash depicted along with polyarticular arthralgias. Laboratory investigation revealed anemia, leukopenia, a positive antinuclear antibody test (1:1024), and the presence of anti-double-stranded DNA antibodies. A skin biopsy shows dense lymphocytic infiltrate at the dermo-epidermal junction and around hair follicles. She smokes one pack of cigarettes per day and drinks socially. Family and past medical histories are non-contributory.
Based solely on this patient's underlying medical illness, her increased lifetime risk of which of these internal malignancies is least likely:






