|Poll|April 1, 2011

Rapidly Growing Pedal Lesions Following Chemotherapy

Author(s)Ted Rosen, MD

A 20-year-old woman was receiving a multi-agent chemotherapeutic regimen for Hodgkin disease, stage IIB. After the third round of treatment, she presented for medical care because of rapidly growing pedal lesions that made walking painfully difficult.

What would be the best initial intervention in this case?

A. Amputation of the affected great toe.
B. Immediate excision of the lesions utilizing proton-beam radiosurgery.
C. Application of honey three times daily.
D. Destructive debulking followed by topical antiviral therapy.

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