Annekathryn Goodman, MD, FACS | Authors

Cytoreductive Surgery for Advanced Ovarian Cancer: Quo Vadis?

September 15, 2011

This article focuses on the recent debate regarding when-or whether-patients with ovarian cancer should undergo aggressive surgical resection.

Surgical Cytoreduction in Ovarian Cancer

May 01, 2004

Tumor resection without expectationof complete excision violatesthe traditional tenets ofsurgical oncology. The concept of operabilitycarries the implication ofcomplete tumor excision with a marginof normal tissue. This classic viewwas challenged by Griffith’s landmark1975 paper showing an improved survivalwith surgical cytoreduction-atechnique that cut across tumor andrarely attained negative margins.[1] Heshowed in 70 patients that survival timewas inversely proportional to the sizeof the residual tumor after surgery.