Author | Dina Ibrahim, MD

Articles

Gemcitabine and UFT Plus Oral Calcium Folinate: Phase I Study

July 01, 1999

ByPhilip Agop Philip, MD, PhD, FRCP|Dina Ibrahim, MD|Mark Zalupski, MD|Anthony Shields, MD, PhD

Gemcitabine (Gemzar) (2-deoxy-2,2-difluorocytidine) is a new antimetabolite being increasingly used in the treatment of solid tumors. It is an analog of deoxycytidine and cytosine arabinoside (Ara-C) (Figure 1) that has shown significant activity