Author | Jennifer Kelly Shepphird, PhD


Potassium Channel Blockers Show Promise as Treatment for Brain Tumors

August 31, 2015

Highly druggable ion channels, which are common therapeutic targets for heart disease and neurological conditions, may represent useful targets in cancer treatment as well, according to researchers from the University of California at San Francisco.

T Cells from Melanoma Lymph Nodes Show Promise for Adoptive Immunotherapy

July 20, 2015

T cells generated from tumor-draining lymph nodes of patients with stage III melanoma were shown to mediate protective immune responses in vivo in a melanoma xenograft model, according to a report published in the Journal of Immunotherapy.

Molecular Predictors May Help Determine Outcome for Melanoma Patients

June 18, 2015

MicroRNA (miRNA) profiling of samples from patients with metastatic melanoma who were treated with carboplatin/paclitaxel (CP) identified significantly higher expression of a specific microRNA (miR-659-3p) that was associated with longer progression-free survival (P = .008).

IL-6 Secretion & ALK Suppression in Advanced Prostate Cancer

June 10, 2015

Prostate cancer cells with a specific mutation profile have been found to secrete IL-6, which in turn activates the oncogene MYC to drive cell proliferation and disease progression.