Mark A. O'Rourke, MD | Authors

Vinorelbine and Carboplatin in the Treatment of Advanced Non-Small-Cell Lung Cancer

October 02, 1997

Randomized trials in patients with advanced non-small-cell lung cancer (NSCLC) have demonstrated that the combination of vinorelbine (Navelbine) and cisplatin

Historical Review of Trials With Vinorelbine in Non-Small-Cell Lung Cancer

October 02, 1997

Two large-scale, randomized, phase III trials have offered new information on the response rates, survival benefits, and safety profile of vinorelbine (Navelbine) in non-small-cell lung cancer (NSCLC). In a multicenter, European trial, the response rate was significantly higher with vinorelbine/cisplatin (Platinol) than with vindesine (Eldisine)/cisplatin (P < .02) or vinorelbine alone (P < .001).