Author | Sridhar Mani, MD

Articles

Novel Combinations With Oxaliplatin

December 01, 2000

BySridhar Mani, MD|Jane Manalo, MD|David Bregman, MD

Oxaliplatin (Eloxatin) is a novel antineoplastic platinum derivative that may exert its cytotoxic effects by blocking DNA replication/transcription, thus resulting in cell death in proliferating cells, as well as apoptosis.

UFT Plus Leucovorin in Advanced Hepatobiliary Tumors and Pancreatic Adenocarcinomas

September 02, 1997

BySridhar Mani, MD

UFT (tegafur and uracil) has been studied extensively in Japan, with documented efficacy in hepatobiliary and pancreatic cancer. In the United States, UFT with or without leucovorin has not undergone phase II testing in