Expert Panel: Role of Genomics and Genetics in Prostate Cancer
Christopher Lee, MD; Alvaro Martinez, MD; Daniel Kim, MD, MBA; Steven E. Finkelstein, MD; and Dwight E. Heron, MD, MBA, FACRO, FACR, discuss how genomic and genetic research is revolutionizing our understanding of prostate cancer risk, progression, personalized treatment strategies, and potential targeted interventions by identifying specific genetic markers, inherited mutations, and molecular pathways that influence disease development and patient outcomes.
Panelists discuss how genomic biomarker testing has revolutionized prostate cancer management by enabling a precision medicine approach that transitions from population-based treatments to individualized therapeutic strategies based on precise molecular profiling.
Panelists discuss how advanced multi-omics approaches, personalized precision medicine techniques, artificial intelligence–driven genetic interpretation tools, and emerging gene editing technologies such as CRISPR (clustered regularly interspaced short palindromic repeats) are poised to revolutionize clinical practice by enabling more targeted diagnostics, predictive risk assessments, and individualized treatment strategies across oncology, rare disease management, and chronic condition prevention.
Panelists discuss how genomic testing has revolutionized patient selection for active surveillance by integrating molecular insights that transcend traditional clinical parameters, enabling more nuanced risk stratification and personalized management of intermediate-risk prostate cancer.
EP. 4: CCR Scores and Beyond: Precision Strategies for Treatment Intensification in Prostate Cancer
Panelists discuss how emerging genomic risk stratification tools such as the clinical cell-cycle risk (CCR) score are transforming personalized prostate cancer treatment by enabling more nuanced assessments of metastasis risk and treatment intensification strategies beyond traditional NCCN risk groupings.
Panelists discuss how Prolaris distinguishes itself from other genomic biomarker platforms by providing uniquely actionable clinical information that quantifies the absolute benefit of androgen deprivation therapy when added to radiation therapy, offering clinicians a more precise tool for personalizing prostate cancer treatment strategies.
