Oncology Vol 30 No 3

Chemotherapy-Induced Peripheral Neuropathy

March 15, 2016

Chemotherapy-induced peripheral neuropathy (CIPN) is a common treatment-related side effect of several widely used drugs. Agents known to cause CIPN include platinum analogs, antitubulins, proteasome inhibitors, immunomodulatory agents, and some of the newer biologics.

Vaccine Therapies Against Gliomas: Prime Time Yet?

March 15, 2016

The promise of vaccine-based anticancer therapies has been explored for a number of years. However, the research met with little success in its early phases, largely because of a poor understanding of the biology of the immune system and its role in combatting cancer.

More Opaque Than Clear: Reality Is Always Cloaked in Shades of Gray

March 15, 2016

Lung cancer exhibits a wide spectrum of behavior, from inconsequential to nonaggressive, typically aggressive, and very aggressive lung cancer. The proportion of “well-behaved” cancers has clearly been increased by the advent of CT screening.

HPV and Penile Cancer: Perspectives on the Future Management of HPV-Positive Disease

March 15, 2016

Over the past 5 years, several studies have investigated the molecular profiling of penile carcinomas, examining both genomic and epigenetic alterations. These studies have revealed distinct molecular pathways associated with HPV status.

The Quest for an Evidence-Based Approach to Intermediate-Risk Prostate Cancer

March 15, 2016

We must now come to a uniform consensus regarding the descriptions of these risk groups in order to truly determine which treatments have the best oncologic efficacy, while minimizing overtreatment and optimizing patients’ quality of life.