A 63-Year-Old Male Hospitalized Following Massive Hemorrhage

Poll

A 63-year-old male was hospitalized following a massive hemorrhage secondary to a motor vehicle accident and subsequent infection of a surgical site. Three weeks post-admittance his white blood cells (WBC) demonstrated a marked elevation (40,000/mm3). Subsequent laboratory tests showed a very high leukocyte alkaline phosphatase score, whereas the PCR for the BCR-ABL fusion gene was negative. Click here to see the whole slide image.

Click here for the comparative pathology.

What is your most likely diagnosis?

A. Chronic Myeloid Leukemia (CML)
B. Acute Myeloid Leukemia (AML)
C. Leukemoid reaction