
A positive CHMP opinion supports the perioperative use of pembrolizumab plus enfortumab vedotin in resectable MIBC regardless of cisplatin eligibility.
A 41-year-old male carrying the diagnosis of Peutz-Jeghers syndrome complains of upper abdominal pain radiating to the back and a 15-pound weight loss. Laboratory studies and imaging prompt surgery. Tissue obtained from the surgery reveals the slide above:
Your diagnosis is:



!["Patients [with cancer] and physicians would rather have a fixed-duration treatment, if possible," said Julie M. Vose, MD, MBA, at SOHO 2026.](https://cdn.sanity.io/images/0vv8moc6/cancernetwork/1cfb57db416943d8f8690afb0bc0d13aa3d90683-400x400.jpg?w=350&fit=crop&auto=format)

