Carcinoma of the Lung

A 63-year-old male with a 50 pack-year smoking history presents with shortness of breath, coughing, and blood-streaked sputum. A chest radiograph shows a large mass in the middle lobe of the right lung that is biopsied, and the H&E–stained slide is seen above. Click here to see the whole slide image.

Click here for the comparative pathology.

Your diagnosis is: