What Caused This Mediastinal Mass in a 42-Year-Old Man?


A patient with a history of thalassemia minor presents with chest pain and a cough. Imaging shows a posterior mediastinal mass. A biopsy is performed. What is your diagnosis?

A 42-year-old man presents with chest pain and a cough. Diagnostic imaging reveals a posterior mediastinal mass. Importantly, the patient has a history of thalassemia minor. A biopsy of the mass is performed.

Based on the image shown, what is your diagnosis?

A. Liposarcoma
B. Malignant fibrous histiocytoma
C. Neurogenic sarcoma
D. Extramedullary hematopoiesis (myelolipoma)