Ajithkumar Puthillath, MD | Authors

2025 MORSE AVE

Sacramento

95831-4329

Articles

Neoadjuvant Chemoradiation for Rectal Cancer: Is More Better?

June 02, 2008

Neoadjuvant chemoradiation has become the favored adjuvant treatment for stages II and III rectal cancer. Compared to postoperative chemoradiation, this modality of treatment has been shown to be superior in terms of toxicity, local relapse, and sphincter-saving.[1] This article will focus on the evolution of neoadjuvant chemotherapy over the past 2 decades, current acceptable neoadjuvant standards, and current investigational regimens.