Aminah Jatoi, MD | Authors

Anorexia and Cachexia

June 01, 2015

Many patients with advanced cancer undergo a wasting syndrome associated with cancer anorexia/cachexia and asthenia. In defining these terms a bit further, anorexia is associated with a marked loss of appetite and/or an aversion to food.

In Search of Rigorous Data on How to Palliate the EGFR Inhibitor–Induced Rash

February 19, 2009

Epidermal growth factor receptor (EGFR) inhibitors have emerged as important drugs in cancer therapy, providing a proven survival advantage for some patients with non–small-cell lung cancer, colorectal cancer, head and neck cancer, and pancreas cancer.

Commentary (Jatoi/Loprinzi): Obesity and Cancer: The Risks, Science, and Potential Management Strategies

June 01, 2005

Dr. McTiernan provides a comprehensive,thoughtful overviewof several studies thathave focused on obesity and cancer.She discusses the preponderance ofdata that have shown both a directrelationship between obesity and thedevelopment of cancer as well as adirect relationship between obesityand cancer recurrence. Although bothrelationships are clinically relevant,the latter is particularly important tocancer health-care providers. Today,more than ever before, cancer patientsare diagnosed early and treated effectively,thereby yielding a sizable cohortof cancer survivors and potentialcancer survivors.[1] Understandingthe relationship between obesity oroverweight status and cancer recurrenceis now more timely than it hasever been.

Introduction: Why Should We Care About the Cancer Anorexia/Weight Loss Syndrome?

February 01, 2003

In a recent study, Wolfe and others interviewed 103parents of children who had died from cancer.[1]Approximately 80% of these children suffered anorexia,or loss of appetite. Over 35% of parents identifiedanorexia as a cause of distress for their child whena physician failed to recognize it. Wolfe and othersconcluded,"greater attention to symptomcontrol.…might ease…suffering." In adults, the syndromeof cancer anorexia/weight loss is no lesspervasive, and no less distressing. Anorexia is one ofthe most deleterious symptoms, surpassed only bypain and fatigue.[2] The majority of adults withadvanced cancer suffer from it toward the end of life.Among all cancer patients-regardless of age orcancer type-"greater attention to [the anorexia/weightloss syndrome]…might ease…suffering."

Current Management of Cancer-Associated Anorexia and Weight Loss

April 01, 2001

Loss of appetite and weight predict a poor prognosis for cancer patients. Although caloric supplementation might benefit subgroups of patients-specifically, perioperative, severely malnourished cancer patients, stem cell and