Gerard Bastian, PhD | Authors

Impact of UFT on Tumoral TS and DPD Levels in Colorectal Cancer

October 01, 2000

This was an open lable, pilot translational clinical pharmacology study of a brief (7 day) course of UFT, 300 mg/m²/day, in combination with leucovorin, 90 mg/day, in six patients with newly diagnosed advanced colorectal cancer.

European Experience With Irinotecan Plus Fluorouracil/Folinic Acid or Mitomycin

August 01, 1998

Tremendous progress has been made in the medical treatment of advanced colorectal cancer during the past 2 to 3 years, due to the availability of several new drugs. Of these new agents, irinotecan (CPT-11 [Camptosar]) seems